The R language: an engine for bioinformatics and data science

FM Giorgi, C Ceraolo, D Mercatelli - Life, 2022 - mdpi.com
The R programming language is approaching its 30th birthday, and in the last three decades
it has achieved a prominent role in statistics, bioinformatics, and data science in general. It …

Natural products for drug discovery in the 21st century: innovations for novel drug discovery

NE Thomford, DA Senthebane, A Rowe… - International journal of …, 2018 - mdpi.com
The therapeutic properties of plants have been recognised since time immemorial. Many
pathological conditions have been treated using plant-derived medicines. These medicines …

Current applications and future impact of machine learning in radiology

G Choy, O Khalilzadeh, M Michalski, S Do, AE Samir… - Radiology, 2018 - pubs.rsna.org
Recent advances and future perspectives of machine learning techniques offer promising
applications in medical imaging. Machine learning has the potential to improve different …

To metabolomics and beyond: a technological portfolio to investigate cancer metabolism

F Danzi, R Pacchiana, A Mafficini, MT Scupoli… - … and Targeted Therapy, 2023 - nature.com
Tumour cells have exquisite flexibility in reprogramming their metabolism in order to support
tumour initiation, progression, metastasis and resistance to therapies. These reprogrammed …

[HTML][HTML] The role of natural products as sources of therapeutic agents for innovative drug discovery

K Dzobo - Comprehensive pharmacology, 2022 - ncbi.nlm.nih.gov
Emerging threats to human health require a concerted effort in search of both preventive and
treatment strategies, placing natural products at the center of efforts to obtain new therapies …

Toward a literature‐driven definition of big data in healthcare

E Baro, S Degoul, R Beuscart… - BioMed research …, 2015 - Wiley Online Library
Objective. The aim of this study was to provide a definition of big data in healthcare.
Methods. A systematic search of PubMed literature published until May 9, 2014, was …

Genetics and epigenetics in allergic rhinitis

BY Choi, M Han, JW Kwak, TH Kim - Genes, 2021 - mdpi.com
The pathogenesis of allergic rhinitis is associated with genetic, environmental, and
epigenetic factors. Genoty** of single nucleotide polymorphisms (SNPs) is an advanced …

Integrative methods for analyzing big data in precision medicine

V Gligorijević, N Malod‐Dognin, N Pržulj - Proteomics, 2016 - Wiley Online Library
We provide an overview of recent developments in big data analyses in the context of
precision medicine and health informatics. With the advance in technologies capturing …

Informatics for chemistry, biology, and biomedical sciences

E López-López, J Bajorath… - Journal of chemical …, 2020 - ACS Publications
Informatics is growing across disciplines, impacting several areas of chemistry, biology, and
biomedical sciences. Besides the well-established bioinformatics discipline, other …

Metabolomics technology and bioinformatics for precision medicine

RK Azad, V Shulaev - Briefings in bioinformatics, 2019 - academic.oup.com
Precision medicine is rapidly emerging as a strategy to tailor medical treatment to a small
group or even individual patients based on their genetics, environment and lifestyle …