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One unique feature of tumors is the presence of hypoxic regions, which occur predominantly
at the tumor center. Hypoxia has a major impact on various aspects of tumor cell function …

Abstract Hyperbaric oxygen (HBO) treatment promotes early recovery from muscle injury.
Reactive oxygen species (ROS) upregulation is a key mechanism of HBO, which produces …

Stem cell therapy has the potential to regenerate heart tissue damaged by myocardial
infarction (MI), but it experiences extremely low efficacy. One of the major causes is the …

Our previous studies have demonstrated that hyperbaric oxygen (HBO) preconditioning
induces tolerance to focal cerebral ischemia. The present study aimed to investigate …

Background Use of dermal fillers for soft tissue augmentation has become an integral part of
aesthetic practices. Dermal fillers temporarily remove the appearance of rhytids and reduce …

Neuroprotective drugs have so far failed clinical trials, at high cost, and intravenous tissue
plasminogen activator (iv tPA) remains the only FDA-approved acute stroke therapy …

We studied the effect of hyperbaric oxygen (HBO) preconditioning on the molecular
mechanisms of neuroprotection in a rat focal cerebral ischemic model. Seventy-two male …

Background and Purpose—Hyperbaric oxygen (HBO) has been reported to be
neuroprotective and to improve neurofunctional outcomes in acute stroke. However, it is not …

Cell death and the clearance of apoptotic cells are tightly regulated by various signaling
molecules in order to maintain physiological tissue function and homeostasis. The …