Breast cancer is the most commonly diagnosed cancer in women. Metastasis is the primary
cause of mortality for breast cancer patients. Multiple mechanisms underlie breast cancer …

In vitro tumor models have provided important tools for cancer research and serve as low-
cost screening platforms for drug therapies; however, cancer recurrence remains largely …

Myeloid-derived suppressor cells are a heterogeneous group of pathologically activated
immature cells that play a major role in the negative regulation of the immune response in …

Breast cancer is the most commonly diagnosed cancer and second-leading cause of cancer
deaths in women. Breast cancer stem cells (BCSCs) promote metastasis and therapeutic …

DNA targeting anticancer agents have been very successful in clinic, especially, when used
in combinatorial therapy. But unfortunately, they often exhibit high levels of toxicity towards …

Signal transducer and activator of transcription 3 (STAT3) plays crucial roles in several
cellular processes such as cell proliferation and survival, and has been found to be …

Aldehyde dehydrogenases (ALDHs) are a family of detoxifying enzymes often upregulated
in cancer cells and associated with therapeutic resistance. In humans, the ALDH family …

Functionalized drug delivery systems against malignant lung metastasis of breast cancer
have been extensively studied, while metastasis remains a challenging issue. We propose a …

Abstract Development of an effective treatment against advanced tumors remains a major
challenge for cancer immunotherapy. We have previously developed a potent mannose …

Signal transducer and activator of transcription 3 (STAT3) controls many biological
processes including differentiation, survival, proliferation, and angiogenesis. In normal …