Advanced methods for natural products discovery: bioactivity screening, dereplication, metabolomics profiling, genomic sequencing, databases and informatic tools …

SP Gaudêncio, E Bayram, L Lukić Bilela, M Cueto… - Marine drugs, 2023 - mdpi.com
Natural Products (NP) are essential for the discovery of novel drugs and products for
numerous biotechnological applications. The NP discovery process is expensive and time …

Drug development, Brazilian biodiversity and political choices: Where are we heading?

PMP Ferreira, DDR Arcanjo… - Journal of Toxicology and …, 2023 - Taylor & Francis
The aim of this review was to (i) acknowledge structural advantages of natural products
(NPs) for designing therapeutic drugs;(ii) emphasize how wildlife conservation is socially …

From the sea to aquafeed: A perspective overview

OT Eroldoğan, B Glencross, L Novoveska… - Reviews in …, 2023 - Wiley Online Library
Aquaculture has been one of the fastest‐growing food production systems sectors for over
three decades. With its growth, the demand for alternative, cheaper and high‐quality feed …

[HTML][HTML] Seaweeds in the oncology arena: Anti-cancer potential of fucoidan as a drug—A review

JO **, D Yadav, K Madhwani, N Puranik, V Chavda… - Molecules, 2022 - mdpi.com
Marine natural products are a discerning arena to search for the future generation of
medications to treat a spectrum of ailments. Meanwhile, cancer is becoming more ubiquitous …

[HTML][HTML] Marine pyrrole alkaloids

K Seipp, L Geske, T Opatz - Marine Drugs, 2021 - mdpi.com
Nitrogen heterocycles are essential parts of the chemical machinery of life and often reveal
intriguing structures. They are not only widespread in terrestrial habitats but can also …

Natural compounds-based nanomedicines for cancer treatment: Future directions and challenges

T Andreani, R Cheng, K Elbadri, C Ferro… - Drug Delivery and …, 2024 - Springer
Several efforts have been extensively accomplished for the amelioration of the cancer
treatments using different types of new drugs and less invasives therapies in comparison …

Identification of pyrrolo [3′, 4': 3, 4] cyclohepta [1, 2-d][1, 2] oxazoles as promising new candidates for the treatment of lymphomas

M Barreca, V Spanò, R Rocca, R Bivacqua… - European journal of …, 2023 - Elsevier
Unsatisfactory outcomes for relapsed/refractory lymphoma patients prompt continuing efforts
to develop new therapeutic strategies. Our previous studies on pyrrole-based anti …

[HTML][HTML] Anticancer activities of marine-derived phenolic compounds and their derivatives

D Matulja, F Vranješević, M Kolympadi Markovic… - Molecules, 2022 - mdpi.com
Since the middle of the last century, marine organisms have been identified as producers of
chemically and biologically diverse secondary metabolites which have exerted various …

Combination of marine bioactive compounds and extracts for the prevention and treatment of chronic diseases

B Ebrahimi, S Baroutian, J Li, B Zhang, T Ying… - Frontiers in …, 2023 - frontiersin.org
Background In recent years, marine-based functional foods and combination therapy are
receiving greater recognition for their roles in healthy lifestyle applications and are being …

Tumor immune microenvironment and genetic alterations in mesothelioma

S Hiltbrunner, L Mannarino, MB Kirschner… - Frontiers in …, 2021 - frontiersin.org
Malignant pleural mesothelioma (MPM) is a rare and fatal disease of the pleural lining. Up to
80% of the MPM cases are linked to asbestos exposure. Even though its use has been …