Protein glycosylation involves the co-translational or post-translational addition of glycans to
proteins and is a crucial protein modification in health and disease. The aim of …

We report proteogenomic analysis of diffuse gastric cancers (GCs) in young populations.
Phosphoproteome data elucidated signaling pathways associated with somatic mutations …

Mass spectrometry based proteomics and other technologies have matured to enable
routine quantitative, system-wide analysis of concentrations, modifications, and interactions …

Formalin-fixed paraffin-embedded (FFPE) tissues are a valuable resource for retrospective
clinical studies. Here, we evaluate the feasibility of (phospho-) proteomics on FFPE lung …

Pseudogenes are mutated copies of protein-coding genes that cannot be translated into
proteins, but a small subset of pseudogenes has been detected at the protein level …

Hydrogen-bonded organic frameworks (HOFs) have emerged as a promising class of
materials for applications of separation and enrichment. Utilizing multiple-ligands to …

In mammals there are at least 10 isoforms of diacylglycerol kinases (DGK). All catalyze the
phosphorylation of diacylglycerol (DAG) to phosphatidic acid (PA). Among DGK isoforms …

Background Cisplatin-based chemotherapy is currently part of the standard of care for
bladder cancer (BC). Unfortunately, some patients respond poorly to chemotherapy and …

Mass-spectrometry-based phosphoproteomic workflows traditionally require efficient
prefractionation and enrichment of phosphopeptides to gain an in-depth, global, and …

Background Prostate cancer is a major public health issue, mainly because patients relapse
after androgen deprivation therapy. Proteomic strategies, aiming to reflect the functional …