Dental enamel is a specialized tissue that has adapted over millions of years of evolution to
enhance the survival of a variety of species. In humans, enamel evolved to form the exterior …

Amelogenesis imperfecta (AI) is one of the typical dental genetic diseases in human. It can
occur isolatedly or as part of a syndrome. Previous reports have mainly clarified the types …

Amelogenesis imperfecta (AI) is a heterogeneous group of genetic rare diseases disrupting
enamel development (Smith et al., Front Physiol, 2017a, 8, 333). The clinical enamel …

Weighted correlation network analysis (WGCNA) is a statistical method that has been widely
used in recent years to explore gene co-expression modules. Competing endogenous RNA …

Gingival conditions and tooth sensitivity of young patients with amelogenesis imperfecta lack
in depth studies. This case-control study aimed to compare (1) the gingival inflammation, the …

Ctip2/Bcl11b is a zinc finger transcription factor with dual action (repression/activation) that
couples epigenetic regulation to gene transcription during the development of various …

Dental enamel is hardest tissue in the body and is produced by dental epithelial cells
residing in the tooth. Their cell fates are tightly controlled by transcriptional programs that are …

Amelogenesis imperfecta (AI) is a heterogeneous group of rare genetic disorders affecting
tooth enamel formation. Here we report an identification of a novel de novo missense …