Background: Thiazole is a good pharmacophore nucleus due to its various pharmaceutical
applications. Its derivatives have a wide range of biological activities such as antioxidant …

Background Thiazole ring is one of the most important heterocycle scaffolds in organic and
medicinal chemistry due to this scaffold being the backbone of numerous drugs and their …

The increasing incidence of microbial resistance and newly emerging pathogens have
become a serious challenge for public health. More and more efforts have been directed to …

Microbial resistance is a big concern worldwide, making the development of new
antimicrobial drugs difficult. The thiazole and pyrazole rings are important heterocyclic …

Pyrazoles, thiazoles and fused thiazoles have been reported to possess many biological
activities. 3-Methyl-5-oxo-4-(2-arylhydrazono)-4, 5-dihydro-1 H-pyrazole-1-carbothioamides …

A series of various substituted thiazole-pyrazole hybrids 5, 7, 8, and 9 were synthesized, and
their chemical structures were confirmed by spectral data (infrared, 1 H & 13 C NMR and …

Thiazole-substituted pyrazole is an important structural feature of many bioactive
compounds, including antiviral, antitubercular, analgesic and anticancer agents. Herein we …

Mycobacterium tuberculosis (Mtb) is an obligate aerobe that is capable of long-term
persistence under conditions of low oxygen tension. A series of thiazolyl-pyrazole …

A series of 1-substituted benzyl-4-[1-phenyl-3-(4-methyl-2-aryl-1, 3-thiazol-5-yl)-1H-pyrazol-
4-yl]-1H-1, 2, 3-triazole derivatives (7a-y) have been synthesized by click reaction of 5-(4 …

A new series of N-aryl-4-(1, 3-diaryl-1H-pyrazol-4-yl) thiazol-2-amine,(8a-x) have been
synthesized by a cyclo-condensation reaction of 2-bromo-1-(1, 3-diphenyl-1H-pyrazol-4-yl) …