Metabolic engineering of Escherichia coli for natural product biosynthesis

D Yang, SY Park, YS Park, H Eun, SY Lee - Trends in Biotechnology, 2020 - cell.com
Natural products are widely employed in our daily lives as food additives, pharmaceuticals,
nutraceuticals, and cosmetic ingredients, among others. However, their supply has often …

Aquaculture industry prospective from gut microbiome of fish and shellfish: An overview

AD Diwan, SN Harke, Gopalkrishna… - Journal of animal …, 2022 - Wiley Online Library
The microbiome actually deals with micro‐organisms that are associated with indigenous
body parts and the entire gut system in all animals, including human beings. These …

CRISPR/Cas9 advances engineering of microbial cell factories

T Jakočiūnas, MK Jensen, JD Keasling - Metabolic engineering, 2016 - Elsevier
One of the key drivers for successful metabolic engineering in microbes is the efficacy by
which genomes can be edited. As such there are many methods to choose from when …

[HTML][HTML] Develo** fungal heterologous expression platforms to explore and improve the production of natural products from fungal biodiversity

X Meng, Y Fang, M Ding, Y Zhang, K Jia, Z Li… - Biotechnology …, 2022 - Elsevier
Natural products from fungi represent an important source of biologically active metabolites
notably for therapeutic agent development. Genome sequencing revealed that the number …

Engineering microbial factories for synthesis of value-added products

J Du, Z Shao, H Zhao - Journal of Industrial Microbiology and …, 2011 - academic.oup.com
Microorganisms have become an increasingly important platform for the production of drugs,
chemicals, and biofuels from renewable resources. Advances in protein engineering …

Metabolic engineering of microorganisms for the synthesis of plant natural products

J Marienhagen, M Bott - Journal of biotechnology, 2013 - Elsevier
Of more than 200,000 plant natural products known to date, many demonstrate important
pharmacological activities or are of biotechnological significance. However, isolation from …

Recent advances in the heterologous expression of microbial natural product biosynthetic pathways

SE Ongley, X Bian, BA Neilan, R Müller - Natural product reports, 2013 - pubs.rsc.org
Covering: up to 2013The heterologous expression of microbial natural product biosynthetic
pathways coupled with advanced DNA engineering enables optimisation of product yields …

Genetic engineering of modular PKSs: from combinatorial biosynthesis to synthetic biology

KJ Weissman - Natural product reports, 2016 - pubs.rsc.org
Covering: up to 2015 Multienzyme polyketide synthases (PKSs) are molecular-scale
assembly lines which construct complex natural products in bacteria. The underlying …

Engineering microbial hosts for production of bacterial natural products

MM Zhang, Y Wang, EL Ang, H Zhao - Natural product reports, 2016 - pubs.rsc.org
Covering up to end 2015 Microbial fermentation provides an attractive alternative to
chemical synthesis for the production of structurally complex natural products. In most cases …

Methylobacterium extorquens: methylotrophy and biotechnological applications

AM Ochsner, F Sonntag, M Buchhaupt… - Applied Microbiology …, 2015 - Springer
Methylotrophy is the ability to use reduced one-carbon compounds, such as methanol, as a
single source of carbon and energy. Methanol is, due to its availability and potential for …