Potential adverse effects of resveratrol: A literature review

A Shaito, AM Posadino, N Younes, H Hasan… - International journal of …, 2020‏ - mdpi.com
Due to its health benefits, resveratrol (RE) is one of the most researched natural
polyphenols. Resveratrol's health benefits were first highlighted in the early 1990s in the …

P-glycoprotein: New insights into structure, physiological function, regulation and alterations in disease

IIA Juvale, AAA Hamid, KB Abd Halim, ATC Has - Heliyon, 2022‏ - cell.com
The multidrug resistance phenomenon presents a major threat to the pharmaceutical
industry. This resistance is a common occurrence in several diseases and is mediated by …

The role of polyphenols in overcoming cancer drug resistance: A comprehensive review

P Maleki Dana, F Sadoughi, Z Asemi… - Cellular & Molecular …, 2022‏ - Springer
Chemotherapeutic drugs are used to treat advanced stages of cancer or following surgery.
However, cancers often develop resistance against drugs, leading to failure of treatment and …

[HTML][HTML] Resveratrol provides neuroprotection by regulating the JAK2/STAT3/PI3K/AKT/mTOR pathway after stroke in rats

Y Hou, K Wang, W Wan, Y Cheng, X Pu, X Ye - Genes & diseases, 2018‏ - Elsevier
Ischemic stroke is a common disease with high mortality and morbidity worldwide. One of
the important pathophysiological effects of ischemic stroke is apoptosis. A neuroprotective …

Mechanisms of drug resistance in acute myeloid leukemia

J Zhang, Y Gu, B Chen - OncoTargets and therapy, 2019‏ - Taylor & Francis
Acute myeloid leukemia (AML) is a kind of malignant hematopoietic system disease
characterized by abnormal proliferation, poor cell differentiation, and infiltration of bone …

[HTML][HTML] The Nrf2 pathway in ischemic stroke: a review

M Farina, LE Vieira, B Buttari, E Profumo, L Saso - Molecules, 2021‏ - mdpi.com
Ischemic stroke, characterized by the sudden loss of blood flow in specific area (s) of the
brain, is the leading cause of permanent disability and is among the leading causes of death …

Dioscin: A diverse acting natural compound with therapeutic potential in metabolic diseases, cancer, inflammation and infections

X Tao, L Yin, L Xu, J Peng - Pharmacological Research, 2018‏ - Elsevier
Currently, the numbers of patients with cancer, fibrosis, diabetes, chronic kidney disease,
stroke and osteoporosis are increasing fast and fast. It's critical necessary to discovery lead …

[HTML][HTML] A Review of the Ethnomedicinal Uses, Biological Activities, and Triterpenoids of Euphorbia Species

D Kemboi, X Peter, M Langat, J Tembu - Molecules, 2020‏ - mdpi.com
The genus Euphorbia is one of the largest genera in the spurge family, with diversity in
range, distribution, and morphology. The plant species in this genus are widely used in …

[HTML][HTML] Mesenchymal stem cell-associated lncRNA in osteogenic differentiation

C Ju, R Liu, YW Zhang, Y Zhang, R Zhou, J Sun… - Biomedicine & …, 2019‏ - Elsevier
Mesenchymal stem cells (MSCs) have the ability to differentiate into multiple cell types,
including osteogenic, chondrogenic and adipogenic lineages. Osteogenic differentiation of …

Disease-associated regulation of gene expression by resveratrol: Special focus on the PI3K/AKT signaling pathway

S Ghafouri-Fard, Z Bahroudi, H Shoorei… - Cancer Cell …, 2022‏ - Springer
Abstract Resveratrol (3, 5, 4′-trihydroxy-trans-stilbene) is a natural phenol that is present in
the skin of the grape, blueberry, raspberry, mulberry, and peanut. This substance is …