A review of chemical signaling pathways in the quorum sensing circuit of Pseudomonas aeruginosa

K Vadakkan, AK Ngangbam, K Sathishkumar… - International Journal of …, 2024 - Elsevier
Pseudomonas aeruginosa, an increasingly common competitive and biofilm organism in
healthcare infection with sophisticated, interlinked and hierarchic quorum systems (Las, Rhl …

Biofilm and wound healing: From bench to bedside

AG Goswami, S Basu, T Banerjee… - European journal of …, 2023 - Springer
The bubbling community of microorganisms, consisting of diverse colonies encased in a self-
produced protective matrix and playing an essential role in the persistence of infection and …

EEF2-inactivating toxins engage the NLRP1 inflammasome and promote epithelial barrier disruption

M Pinilla, R Mazars, R Vergé, L Gorse… - Journal of Experimental …, 2023 - rupress.org
Human airway and corneal epithelial cells, which are critically altered during chronic
infections mediated by Pseudomonas aeruginosa, specifically express the inflammasome …

Pseudomonas aeruginosa breaches respiratory epithelia through goblet cell invasion in a microtissue model

AL Swart, BJ Laventie, R Sütterlin, T Junne… - Nature …, 2024 - nature.com
Pseudomonas aeruginosa, a leading cause of severe hospital-acquired pneumonia, causes
infections with up to 50% mortality rates in mechanically ventilated patients. Despite some …

An anti-biofilm cyclic peptide targets a secreted aminopeptidase from P. aeruginosa

CJ Harding, M Bischoff, M Bergkessel… - Nature Chemical …, 2023 - nature.com
Pseudomonas aeruginosa is an opportunistic pathogen that causes serious illness,
especially in immunocompromised individuals. P. aeruginosa forms biofilms that contribute …

[HTML][HTML] Advancing engineered approaches for sustainable wound regeneration and repair: Harnessing the potential of green synthesized silver nanoparticles

J Nandhini, E Karthikeyan, EE Rani, VS Karthikha… - Engineered …, 2024 - Elsevier
Wound healing is a crucial biological process for tissue repair and regeneration, preventing
infections and complications. There's been a growing interest in exploring sustainable …

Metallic and metal oxide nanoparticles in treating Pseudomonas aeruginosa infections

DU Kapoor, RJ Patel, M Gaur, S Parikh… - Journal of Drug Delivery …, 2024 - Elsevier
Pseudomonas aeruginosa, a pathogenic microorganism of substantial clinical concern, has
exhibited a remarkable ability to cause diverse infections, particularly in …

[HTML][HTML] What's old is new again: Insights into diabetic foot microbiome

AAH Rajab, WAH Hegazy - World Journal of Diabetes, 2023 - ncbi.nlm.nih.gov
Diabetes is a chronic disease that is considered one of the most stubborn global health
problems that continues to defy the efforts of scientists and physicians. The prevalence of …

Antibiofilm properties of cathelicidin LL-37: an in-depth review

H Memariani, M Memariani - World Journal of Microbiology and …, 2023 - Springer
Notwithstanding ceaseless endeavors toward develo** effective antibiofilm
chemotherapeutics, biofilm-associated infections continue to be one of the most perplexing …

[HTML][HTML] Discovery of highly neutralizing human antibodies targeting Pseudomonas aeruginosa

A Simonis, C Kreer, A Albus, K Rox, B Yuan… - Cell, 2023 - cell.com
Drug-resistant Pseudomonas aeruginosa (PA) poses an emerging threat to human health
with urgent need for alternative therapeutic approaches. Here, we deciphered the B cell and …