Major depressive disorder is a debilitating disorder affecting millions of people each year.
Brain-derived neurotrophic factor (BDNF) and inflammation are two prominent biologic risk …

The suicide death toll is alarmingly high, outnumbering deaths from war and homicide
worldwide (1). Many factors contribute to suicide death, making it difficult to prevent because …

Depression is a common cause of mortality and morbidity, but the biological bases of the
deficits in emotional and cognitive processing remain incompletely understood. Current …

Brain-derived neurotrophic factor (BDNF) has a primary role in neuronal development,
differentiation and plasticity in both the develo** and adult brain. A single-nucleotide …

Suicide is a major public health concern and a leading cause of death in most societies.
Suicidal behaviour is complex and heterogeneous, likely resulting from several causes. It …

Background Brain-derived neurotrophic factor is implicated in the pathophysiology of major
depressive disorder and suicide. Both are partly caused by early life adversity, which …

Schizophrenia is believed to arise from complex gene–environment interactions. Brain-
derived neurotrophic factor (BDNF) is involved in neuronal development, differentiation and …

Depression is a neuropsychiatric disorder affecting a huge percentage of the active
population especially in developed countries. Research has devoted much of its attention to …

With recent studies using genetic, epigenetic, and other molecular and neurochemical
approaches, a new era has begun in understanding pathophysiology of suicide. Emerging …

BACKGROUND: The high prevalence, recurrence rate, chronicity, and illness burden in
bipolar disorder (BD) are well documented. Moreover, insufficient response with …