The protein corona from nanomedicine to environmental science

M Mahmoudi, MP Landry, A Moore… - Nature Reviews Materials, 2023 - nature.com
The protein corona spontaneously develops and evolves on the surface of nanoscale
materials when they are exposed to biological environments, altering their physiochemical …

Mesoporous bioactive glasses in cancer diagnosis and therapy: stimuli‐responsive, toxicity, immunogenicity, and clinical translation

E Sharifi, A Bigham, S Yousefiasl, M Trovato… - Advanced …, 2022 - Wiley Online Library
Cancer is one of the top life‐threatening dangers to the human survival, accounting for over
10 million deaths per year. Bioactive glasses have developed dramatically since their …

Measurements of heterogeneity in proteomics analysis of the nanoparticle protein corona across core facilities

AA Ashkarran, H Gharibi, E Voke, MP Landry… - Nature …, 2022 - nature.com
Robust characterization of the protein corona—the layer of proteins that spontaneously
forms on the surface of nanoparticles immersed in biological fluids—is vital for prediction of …

Scratching the surface of the protein corona: challenging measurements and controversies

PL Latreille, M Le Goas, S Salimi, J Robert… - ACS …, 2022 - ACS Publications
This Review aims to provide a systematic analysis of the literature regarding ongoing
debates in protein corona research. Our goal is to portray the current understanding of two …

Identification of the proteins determining the blood circulation time of nanoparticles

C Marques, MJ Hajipour, C Marets, A Oudot… - ACS …, 2023 - ACS Publications
The therapeutic efficacy and adverse impacts of nanoparticles (NPs) are strongly dependent
on their systemic circulation time. The corona proteins adsorbed on the NPs determine their …

In vivo protein corona on nanoparticles: does the control of all material parameters orient the biological behavior?

N Singh, C Marets, J Boudon, N Millot, L Saviot… - Nanoscale …, 2021 - pubs.rsc.org
Nanomaterials have a huge potential in research fields from nanomedicine to medical
devices. However, surface modifications of nanoparticles (NPs) and thus of their …

Nanoscale characterization of the biomolecular corona by cryo-electron microscopy, cryo-electron tomography, and image simulation

S Sheibani, K Basu, A Farnudi, A Ashkarran… - Nature …, 2021 - nature.com
The biological identity of nanoparticles (NPs) is established by their interactions with a wide
range of biomolecules around their surfaces after exposure to biological media …

Magnetic responsive hydroxyapatite scaffold modulated macrophage polarization through PPAR/JAK-STAT signaling and enhanced fatty acid metabolism

X Sun, Y Gao, Z Li, J He, Y Wu - Biomaterials, 2023 - Elsevier
Despite the general observations of bone repair with magnetic cues, the mechanisms of
magnetic cues in macrophage response during bone healing have not been systematically …

In situ characterization techniques of protein corona around nanomaterials

F Fu, D Crespy, K Landfester, S Jiang - Chemical Society Reviews, 2024 - pubs.rsc.org
Nanoparticles (NPs) inevitably interact with proteins upon exposure to biological fluids,
leading to the formation of an adsorption layer known as the “protein corona”. This corona …

Standardizing protein corona characterization in nanomedicine: a multicenter study to enhance reproducibility and data homogeneity

AA Ashkarran, H Gharibi, SM Modaresi, AA Saei… - Nano Letters, 2024 - ACS Publications
We recently revealed significant variability in protein corona characterization across various
proteomics facilities, indicating that data sets are not comparable between independent …