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Repurposing approved non-oncology drugs for cancer therapy: A comprehensive review of mechanisms, efficacy, and clinical prospects
Cancer poses a significant global health challenge, with predictions of increasing
prevalence in the coming years due to limited prevention, late diagnosis, and inadequate …
prevalence in the coming years due to limited prevention, late diagnosis, and inadequate …
Green synthesis of silver nanoparticles and their potential applications in mitigating cancer
In recent years, the field of nanotechnology has brought about significant advancements that
have transformed the landscape of disease diagnosis, prevention, and treatment …
have transformed the landscape of disease diagnosis, prevention, and treatment …
Synthesis and anticancer evaluation of novel indole based arylsulfonylhydrazides against human breast cancer cells
A Gaur, MN Peerzada, NS Khan, I Ali, A Azam - ACS omega, 2022 - ACS Publications
A series of novel indole based sulfonohydrazide derivatives (5a–k) containing morpholine
heterocyclic ring were synthesized through multistep chemical reactions. The target …
heterocyclic ring were synthesized through multistep chemical reactions. The target …
Switchable synthesis of 2-methylene-3-aminoindolines and 2-methyl-3-aminoindoles using calcium carbide as a solid alkyne source
Z Wang, Z Zhang, Z Li - Organic Letters, 2022 - ACS Publications
The one-pot three-component method for the switchable synthesis of 2-methylene-3-
aminoindolines and 2-methyl-3-aminoindoles by reactions of N-(2-formylaryl) sulfonamides …
aminoindolines and 2-methyl-3-aminoindoles by reactions of N-(2-formylaryl) sulfonamides …
Salicylaldehyde-cobalt (II)-catalyzed C–H alkoxylation of indoles with secondary alcohols
MG Huang, YY Tan, MT Ai, XH Chen… - The Journal of Organic …, 2024 - ACS Publications
A straight and efficient protocol for the synthesis of hindered indole-ethers via C–H
alkoxylation of indoles was developed by a cobalt-catalyzed cross-dehydrogenative …
alkoxylation of indoles was developed by a cobalt-catalyzed cross-dehydrogenative …
Ultrasonic energy for construction of bioactive heterocycles
The ultrasonic energy has been revisited and applied for the synthesis of bioactive
molecules in a short time and green method. These compounds can exhibit anticancer …
molecules in a short time and green method. These compounds can exhibit anticancer …
Advances in chalcone derivatives: Unravelling their anticancer potential through structure-activity studies
KA Sheikh, A Gupta, M Umar, R Ali… - Journal of Molecular …, 2024 - Elsevier
Cancer continues to be a global health challenge, thereby necessitating the evolution of
innovative therapeutic strategies. The synthesis of chalcone derivatives has garnered …
innovative therapeutic strategies. The synthesis of chalcone derivatives has garnered …
A comprehensive review on journey of pyrrole scaffold against multiple therapeutic targets
Heterocyclic compounds are that type of substances that are deeply intertwined with
biological processes. Heterocycles are found in about 90% of commercially available …
biological processes. Heterocycles are found in about 90% of commercially available …
Access to polycyclic indole-3, 4-fused nine-membered ring via cascade 1, 6-hydride transfer/cyclization
S Yang, XD An, B Qiu, RB Liu, J **ao - Organic Letters, 2021 - ACS Publications
A cascade aldimine condensation/1, 6-hydride transfer/Mannich-type cyclization of indole-
derived phenylenediamine with aldehydes was developed for one-step construction of a …
derived phenylenediamine with aldehydes was developed for one-step construction of a …
Anticancer Potential of Thymoquinone: A Novel Bioactive Natural Compound from Nigella sativa L.
PA Mir, R Mohi-Ud-Din, N Banday… - Anti-Cancer Agents …, 2022 - benthamdirect.com
Cancer involves the uncontrolled division of cells resulting in abnormal cell growth due to
various gene mutations and is considered the second major cause of death. Due to drug …
various gene mutations and is considered the second major cause of death. Due to drug …