Repurposing approved non-oncology drugs for cancer therapy: A comprehensive review of mechanisms, efficacy, and clinical prospects

R Mohi-Ud-Din, A Chawla, P Sharma, PA Mir… - European journal of …, 2023 - Springer
Cancer poses a significant global health challenge, with predictions of increasing
prevalence in the coming years due to limited prevention, late diagnosis, and inadequate …

Green synthesis of silver nanoparticles and their potential applications in mitigating cancer

RH Mir, M Maqbool, PA Mir, MS Hussain… - Current …, 2024 - benthamdirect.com
In recent years, the field of nanotechnology has brought about significant advancements that
have transformed the landscape of disease diagnosis, prevention, and treatment …

Synthesis and anticancer evaluation of novel indole based arylsulfonylhydrazides against human breast cancer cells

A Gaur, MN Peerzada, NS Khan, I Ali, A Azam - ACS omega, 2022 - ACS Publications
A series of novel indole based sulfonohydrazide derivatives (5a–k) containing morpholine
heterocyclic ring were synthesized through multistep chemical reactions. The target …

Switchable synthesis of 2-methylene-3-aminoindolines and 2-methyl-3-aminoindoles using calcium carbide as a solid alkyne source

Z Wang, Z Zhang, Z Li - Organic Letters, 2022 - ACS Publications
The one-pot three-component method for the switchable synthesis of 2-methylene-3-
aminoindolines and 2-methyl-3-aminoindoles by reactions of N-(2-formylaryl) sulfonamides …

Salicylaldehyde-cobalt (II)-catalyzed C–H alkoxylation of indoles with secondary alcohols

MG Huang, YY Tan, MT Ai, XH Chen… - The Journal of Organic …, 2024 - ACS Publications
A straight and efficient protocol for the synthesis of hindered indole-ethers via C–H
alkoxylation of indoles was developed by a cobalt-catalyzed cross-dehydrogenative …

Ultrasonic energy for construction of bioactive heterocycles

O Kamble, R Chatterjee, R Dandela, S Shinde - Tetrahedron, 2022 - Elsevier
The ultrasonic energy has been revisited and applied for the synthesis of bioactive
molecules in a short time and green method. These compounds can exhibit anticancer …

Advances in chalcone derivatives: Unravelling their anticancer potential through structure-activity studies

KA Sheikh, A Gupta, M Umar, R Ali… - Journal of Molecular …, 2024 - Elsevier
Cancer continues to be a global health challenge, thereby necessitating the evolution of
innovative therapeutic strategies. The synthesis of chalcone derivatives has garnered …

A comprehensive review on journey of pyrrole scaffold against multiple therapeutic targets

RH Mir, PA Mir, R Mohi-Ud-Din… - Anti-Cancer Agents …, 2022 - benthamdirect.com
Heterocyclic compounds are that type of substances that are deeply intertwined with
biological processes. Heterocycles are found in about 90% of commercially available …

Access to polycyclic indole-3, 4-fused nine-membered ring via cascade 1, 6-hydride transfer/cyclization

S Yang, XD An, B Qiu, RB Liu, J **ao - Organic Letters, 2021 - ACS Publications
A cascade aldimine condensation/1, 6-hydride transfer/Mannich-type cyclization of indole-
derived phenylenediamine with aldehydes was developed for one-step construction of a …

Anticancer Potential of Thymoquinone: A Novel Bioactive Natural Compound from Nigella sativa L.

PA Mir, R Mohi-Ud-Din, N Banday… - Anti-Cancer Agents …, 2022 - benthamdirect.com
Cancer involves the uncontrolled division of cells resulting in abnormal cell growth due to
various gene mutations and is considered the second major cause of death. Due to drug …