Biosynthesis of the modified tetrapyrroles—the pigments of life

DA Bryant, CN Hunter, MJ Warren - Journal of Biological Chemistry, 2020 - ASBMB
Modified tetrapyrroles are large macrocyclic compounds, consisting of diverse conjugation
and metal chelation systems and imparting an array of colors to the biological structures that …

Sharing vitamins: Cobamides unveil microbial interactions

OM Sokolovskaya, AN Shelton, ME Taga - Science, 2020 - science.org
BACKGROUND Nearly every plant, animal, and environment on earth is host to a diverse
community of microorganisms that influence each other and their environment …

Interactive tree of life (iTOL) v3: an online tool for the display and annotation of phylogenetic and other trees

I Letunic, P Bork - Nucleic acids research, 2016 - academic.oup.com
Abstract Interactive Tree Of Life (http://itol. embl. de) is a web-based tool for the display,
manipulation and annotation of phylogenetic trees. It is freely available and open to …

Vitamin biosynthesis by human gut butyrate-producing bacteria and cross-feeding in synthetic microbial communities

EC Soto-Martin, I Warnke, FM Farquharson… - MBio, 2020 - Am Soc Microbiol
We investigated the requirement of 15 human butyrate-producing gut bacterial strains for
eight B vitamins and the proteinogenic amino acids by a combination of genome sequence …

Cyanobacteria and eukaryotic algae use different chemical variants of vitamin B12

KE Helliwell, AD Lawrence, A Holzer, UJ Kudahl… - Current Biology, 2016 - cell.com
Eukaryotic microalgae and prokaryotic cyanobacteria are the major components of the
phytoplankton. Determining factors that govern growth of these primary producers, and how …

Uneven distribution of cobamide biosynthesis and dependence in bacteria predicted by comparative genomics

AN Shelton, EC Seth, KC Mok, AW Han… - The ISME …, 2019 - academic.oup.com
The vitamin B12 family of cofactors known as cobamides are essential for a variety of
microbial metabolisms. We used comparative genomics of 11,000 bacterial species to …

Metabolic engineering of Escherichia coli for de novo biosynthesis of vitamin B12

H Fang, D Li, J Kang, P Jiang, J Sun… - Nature communications, 2018 - nature.com
The only known source of vitamin B12 (adenosylcobalamin) is from bacteria and archaea.
Here, using genetic and metabolic engineering, we generate an Escherichia coli strain that …

Two distinct pools of B12 analogs reveal community interdependencies in the ocean

KR Heal, W Qin, F Ribalet… - Proceedings of the …, 2017 - National Acad Sciences
Organisms within all domains of life require the cofactor cobalamin (vitamin B12), which is
produced only by a subset of bacteria and archaea. On the basis of genomic analyses …

Microbiota and aging

SC Bischoff - Current Opinion in Clinical Nutrition & Metabolic …, 2016 - journals.lww.com
Microbiota and aging : Current Opinion in Clinical Nutrition & Metabolic Care Microbiota and
aging : Current Opinion in Clinical Nutrition & Metabolic Care Log in or Register Subscribe to …

Metagenomic and chemical characterization of soil cobalamin production

X Lu, KR Heal, AE Ingalls, AC Doxey… - The ISME …, 2020 - academic.oup.com
Cobalamin (vitamin B12) is an essential enzyme cofactor for most branches of life. Despite
the potential importance of this cofactor for soil microbial communities, the producers and …