Novel methods for liposome preparation

YP Patil, S Jadhav - Chemistry and physics of lipids, 2014 - Elsevier
Liposomes are bilayer vesicles which have found use, among other applications, as drug
delivery vehicles. Conventional techniques for liposome preparation and size reduction …

Modulation of tissue tropism and biological activity of exosomes and other extracellular vesicles: New nanotools for cancer treatment

SAA Kooijmans, RM Schiffelers, N Zarovni… - Pharmacological …, 2016 - Elsevier
Exosomes are naturally secreted nanovesicles that have recently aroused a great interest in
the scientific and clinical community for their roles in intercellular communication in almost …

Preparation of liposomes of defined size distribution by extrusion through polycarbonate membranes

F Olson, CA Hunt, FC Szoka, WJ Vail… - … et Biophysica Acta (BBA …, 1979 - Elsevier
Liposomes of defined size and homogeneity have been prepared by sequential extrusion of
the usual multilamellar vesicles through polycarbonate membranes. The process is easy …

Liposome formulations with prolonged circulation time in blood and enhanced uptake by tumors.

A Gabizon, D Papahadjopoulos - Proceedings of the National Academy of …, 1988 - pnas.org
The rapid clearance of circulating liposomes from the bloodstream, coupled with their high
uptake by liver and spleen, has thus far been an obstacle to any attempts at targeting to …

Liposomal compositions for enhanced retention of bioactive agents

MB Bally, NL Boman, PR Cullis, LD Mayer - US Patent 5,595,756, 1997 - Google Patents
Liposomal compositions encapsulating bioactive agents and having improved circulation
longevity of the agents are disclosed. Such liposomes combine a low pH of the solution in …

Ethanol injection method for hydrophilic and lipophilic drug-loaded liposome preparation

C Jaafar-Maalej, R Diab, V Andrieu… - Journal of liposome …, 2010 - Taylor & Francis
In this article, a hydrophobic (beclomethasone dipropionate; BDP) and a hydrophilic
(cytarabine; Ara-C) drugs have been encapsulated in liposomes in order to be administered …

Nanoscale drug delivery and hyperthermia: the materials design and preclinical and clinical testing of low temperature-sensitive liposomes used in combination with …

CD Landon, JY Park, D Needham… - The open …, 2011 - pmc.ncbi.nlm.nih.gov
The overall objective of liposomal drug delivery is to selectively target drug delivery to
diseased tissue, while minimizing drug delivery to critical normal tissues. The purpose of this …

[BOG][B] Drug delivery systems

VV Ranade, MA Hollinger, JB Cannon - 2003 - taylorfrancis.com
Drug delivery technologies represent a vast and vital area of Research and Development.
The demand for innovative drug delivery systems continues to grow, and this growth …

Preparation of unilamellar liposomes of intermediate size (0.1–0.2 μm) by a combination of reverse phase evaporation and extrusion through polycarbonate …

F Szoka, F Olson, T Heath, W Vail, E Mayhew… - … et Biophysica Acta (BBA …, 1980 - Elsevier
Liposomes can be prepared by a combination of reverse phase evaporation and sequential
extrusion through polycarbonate membranes. The vesicles have diameters in the range 0.05 …

Protection against oxygen toxicity by intravenous injection of liposome-entrapped catalase and superoxide dismutase.

JF Turrens, JD Crapo, BA Freeman - The Journal of clinical investigation, 1984 - jci.org
Survival of rats exposed to 100% oxygen was increased from 69.5+/-1.5 to 118.1+/-9.9 h
(mean+/-SEM, P less than 0.05) when liposomes containing catalase and superoxide …