Small animal research is an essential tool in studying both pharmaceutical biodistribution
and disease progression over time. Furthermore, through the rapid development of in vivo …

Alzheimer's disease (AD) is an irreversible, progressive disease that slowly destroys
cognitive function, such as thinking, remembering, and reasoning, to a level that one cannot …

The use of monolithic scintillator-based photon detectors in positron emission tomography
(PET) has emerged as an attractive alternative to traditional pixelated array designs …

The MOLECUBES β-CUBE scanner is the newest amongst commercially available
preclinical PET scanners for dedicated small animal imaging. The scanner is compact …

Age-related neurodegenerative diseases (NDDs) are associated with the aggregation and
propagation of specific pathogenic protein species (eg, Aβ, α-synuclein). However, whether …

Many radiotherapy research centers have recently installed novel research platforms
enabling the investigation of the radiation response of tumors and normal tissues in small …

We developed a prototype small-animal PET scanner based on depth-encoding detectors
using dual-ended readout of small scintillator elements to produce high and uniform spatial …

A new preclinical PET system based on dSiPMs, called DigiPET, is presented. The system is
based on thin monolithic scintillation crystals and exhibits superior spatial resolution at low …

Translational research is changing the practice of modern medicine and the way in which
health problems are approached and solved. The use of small-animal models in basic and …

In this work, a small animal PET scanner named SIAT aPET was developed using dual-
ended readout depth encoding detectors to simultaneously achieve high spatial resolution …