Regulatory mechanisms and promising applications of quorum sensing-inhibiting agents in control of bacterial biofilm formation

L Zhou, Y Zhang, Y Ge, X Zhu, J Pan - Frontiers in microbiology, 2020 - frontiersin.org
A biofilm is an assemblage of microbial cells attached to a surface and encapsulated in an
extracellular polymeric substance (EPS) matrix. The formation of a biofilm is one of the …

Roles of Two-Component Systems in Pseudomonas aeruginosa Virulence

M Sultan, R Arya, KK Kim - International journal of molecular sciences, 2021 - mdpi.com
Pseudomonas aeruginosa is an opportunistic pathogen that synthesizes and secretes a
wide range of virulence factors. P. aeruginosa poses a potential threat to human health …

Repurposing phytochemicals as anti‐virulent agents to attenuate quorum sensing‐regulated virulence factors and biofilm formation in Pseudomonas aeruginosa

J Chadha, K Harjai, S Chhibber - Microbial biotechnology, 2022 - Wiley Online Library
Unregulated consumption and overexploitation of antibiotics have paved the way for
emergence of antibiotic‐resistant strains and 'superbugs'. Pseudomonas aeruginosa is …

Natural and synthetic molecules with potential to enhance biofilm formation and virulence properties in Pseudomonas aeruginosa

GJ Jeong, F Khan, N Tabassum… - Critical Reviews in …, 2024 - Taylor & Francis
Pseudomonas aeruginosa can efficiently adapt to changing environmental conditions due to
its ubiquitous nature, intrinsic/acquired/adaptive resistance mechanisms, high metabolic …

Antibiofilm and Antivirulence Activities of Gold and Zinc Oxide Nanoparticles Synthesized from Kimchi-Isolated Leuconostoc sp. Strain C2

MG Kang, F Khan, DM Jo, DK Oh, N Tabassum… - Antibiotics, 2022 - mdpi.com
The rapid emergence of antimicrobial resistance (AMR) among bacterial pathogens results
in antimicrobial treatment failure and the high mortality rate associated with AMR. The …

Motility of Vibrio spp.: regulation and controlling strategies

F Khan, N Tabassum, R Anand, YM Kim - Applied microbiology and …, 2020 - Springer
Flagellar motility in bacteria is a highly regulated and complex cellular process that requires
high energy investment for movement and host colonization. Motility plays an important role …

Friends or enemies? The complicated relationship between Pseudomonas aeruginosa and Staphylococcus aureus

DBY Yung, KJ Sircombe, D Pletzer - Molecular Microbiology, 2021 - Wiley Online Library
Abstract Pseudomonas aeruginosa (Pa) and Staphylococcus aureus (Sa) are opportunistic
pathogens that are most commonly co‐isolated from chronic wounds and the sputum of …

New Pqs Quorum Sensing System Inhibitor as an Antibacterial Synergist against Multidrug-Resistant Pseudomonas aeruginosa

J Liu, JS Hou, YQ Chang, LJ Peng… - Journal of Medicinal …, 2021 - ACS Publications
Development of new bacterial biofilm inhibitors as antibacterial synergists is an effective
strategy to solve the resistance of Pseudomonas aeruginosa. In this paper, a series of 3 …

Quantitative Proteomics Reveals the Mechanism of Silver Nanoparticles against Multidrug-Resistant Pseudomonas aeruginosa Biofilms

Y Zhang, X Pan, S Liao, C Jiang, L Wang… - Journal of proteome …, 2020 - ACS Publications
The decline of clinically effective antibiotics has made it necessary to develop more effective
antimicrobial agents, especially for refractory biofilm-related infections. Silver nanoparticles …

Actinomycin D: a novel Pseudomonasaeruginosa quorum sensing inhibitor from the endophyte Streptomycescyaneochromogenes RC1

YX Zeng, JS Liu, YJ Wang, S Tang, DY Wang… - World Journal of …, 2022 - Springer
The infections caused by Pseudomonas aeruginosa are difficult to treat due to its multidrug
resistance. A promising strategy for controlling P. aeruginosa infection is targeting the …