Bone mechanical properties in healthy and diseased states

EF Morgan, GU Unnikrisnan… - Annual review of …, 2018 - annualreviews.org
The mechanical properties of bone are fundamental to the ability of our skeletons to support
movement and to provide protection to our vital organs. As such, deterioration in mechanical …

Diabetes and its effect on bone and fracture healing

H Jiao, E **ao, DT Graves - Current osteoporosis reports, 2015 - Springer
Diabetes mellitus is a metabolic disorder that increases fracture risk, interferes with bone
formation, and impairs fracture healing. Type 1 diabetes mellitus (T1DM) and type 2 …

Effects of reduced energy availability on bone metabolism in women and men

M Papageorgiou, KJ Elliott-Sale, A Parsons, JCY Tang… - Bone, 2017 - Elsevier
Background The short-term effects of low energy availability (EA) on bone metabolism in
physically active women and men are currently unknown. Purpose We evaluated the effects …

Osteoporosis, fractures, and diabetes

P Jackuliak, J Payer - International journal of endocrinology, 2014 - Wiley Online Library
It is well established that osteoporosis and diabetes are prevalent diseases with significant
associated morbidity and mortality. Patients with diabetes mellitus have an increased risk of …

Skeletal metabolism, fracture risk, and fracture outcomes in type 1 and type 2 diabetes

DE Sellmeyer, R Civitelli, LC Hofbauer, S Khosla… - Diabetes, 2016 - diabetesjournals.org
Fracture risk is significantly increased in both type 1 and type 2 diabetes, and individuals
with diabetes experience worse fracture outcomes than normoglycemic individuals. Factors …

Diabetes pharmacotherapy and effects on the musculoskeletal system

E Kalaitzoglou, JL Fowlkes, I Popescu… - … research and reviews, 2019 - Wiley Online Library
Persons with type 1 or type 2 diabetes have a significantly higher fracture risk than age‐
matched persons without diabetes, attributed to disease‐specific deficits in the …

Type 2 diabetes and bone fractures

KF Moseley - Current Opinion in Endocrinology, Diabetes and …, 2012 - journals.lww.com
Current Opinion in Endocrinology, Diabetes and Obesity Log in or Register Subscribe to
journalSubscribe Get new issue alertsGet alerts Secondary Logo Journal Logo Advanced …

Effects of high glucose and high insulin concentrations on osteoblast function in vitro

JS Cunha, VM Ferreira, E Maquigussa, MA Naves… - Cell and tissue …, 2014 - Springer
Bone disease as a consequence of diabetes mellitus (DM) is not fully understood. The
effects of high glucose (30 mM), high insulin (50 nM), or mannitol (30 mM; osmotic control) …

High serum pentosidine but not esRAGE is associated with prevalent fractures in type 1 diabetes independent of bone mineral density and glycaemic control

T Neumann, S Lodes, B Kästner, S Franke… - Osteoporosis …, 2014 - Springer
Fracture risk in type 1 diabetes (T1D) is supposed to be underestimated by bone mineral
density (BMD). Individuals with T1D had more prevalent fractures in a cross-sectional study …

Effects of diabetes on bone material properties

S Lekkala, EA Taylor, HB Hunt, E Donnelly - Current osteoporosis reports, 2019 - Springer
Abstract Purpose of Review Individuals with type 1 and type 2 diabetes mellitus (T1DM,
T2DM) have an increased risk of bone fracture compared to non-diabetic controls that is not …