Effects of the Environment on Developmental Plasticity and Infection Success of Schistosoma Parasites – An Epigenetic Perspective
Evidence of how environmental cues affect the phenotypes of, and compatibility between
Schistosoma mansoni and their hosts come from studies in environmental parasitology and …
Schistosoma mansoni and their hosts come from studies in environmental parasitology and …
[HTML][HTML] Combining bioinformatics, cheminformatics, functional genomics and whole organism approaches for identifying epigenetic drug targets in Schistosoma …
Schistosomiasis endangers the lives of greater than 200 million people every year and is
predominantly controlled by a single class chemotherapy, praziquantel (PZQ). Development …
predominantly controlled by a single class chemotherapy, praziquantel (PZQ). Development …
[HTML][HTML] An Abies procera-derived tetracyclic triterpene containing a steroid-like nucleus core and a lactone side chain attenuates in vitro survival of both Fasciola …
HL Whiteland, A Chakroborty, JE Forde-Thomas… - International Journal for …, 2018 - Elsevier
Two economically and biomedically important platyhelminth species, Fasciola hepatica
(liver fluke) and Schistosoma mansoni (blood fluke), are responsible for the neglected …
(liver fluke) and Schistosoma mansoni (blood fluke), are responsible for the neglected …
The repositioning of epigenetic probes/inhibitors identifies new anti-schistosomal lead compounds and chemotherapeutic targets
KCL Whatley, G Padalino, H Whiteland… - PLoS Neglected …, 2019 - journals.plos.org
Background Praziquantel represents the frontline chemotherapy used to treat
schistosomiasis, a neglected tropical disease (NTD) caused by infection with macro …
schistosomiasis, a neglected tropical disease (NTD) caused by infection with macro …
Epigenetic and parasitological parameters are modulated in EBi3-/- mice infected with Schistosoma mansoni
Schistosoma mansoni adaptive success is related to regulation of replication, transcription
and translation inside and outside the intermediate and definitive host. We hypothesize that …
and translation inside and outside the intermediate and definitive host. We hypothesize that …
[HTML][HTML] Identification of 6-(piperazin-1-yl)-1, 3, 5-triazine as a chemical scaffold with broad anti-schistosomal activities
Background: Schistosomiasis, caused by infection with blood fluke schistosomes, is a
neglected tropical disease of considerable importance in resource-poor communities …
neglected tropical disease of considerable importance in resource-poor communities …
[HTML][HTML] Schistosoma mansoni venom allergen-like protein 6 (SmVAL6) maintains tegumental barrier function
The Schistosoma mansoni venom allergen-like protein (SmVAL) superfamily is a collection
of at least 29 molecules that have been classified into two distinctive groups (Group 1 and …
of at least 29 molecules that have been classified into two distinctive groups (Group 1 and …
Heterochromatin protein 1 (HP1) of Schistosoma mansoni: non-canonical chromatin landscape and oviposition effects
NS da Trindade, MB Valentini, A Rognon… - Memórias do Instituto …, 2024 - hal.science
Heterochromatin protein 1 (HP1) is widespread in several organisms playing a role in
control of gene expression by heterochromatin formation and maintenance of silent …
control of gene expression by heterochromatin formation and maintenance of silent …
Genome wide expression profiling of Echinococcus multilocularis
M Herz - 2021 - opus.bibliothek.uni-wuerzburg.de
Alveolar echinococcosis, which is caused by the metacestode stage of the small fox
tapeworm Echinococcus multilocularis, is a severe zoonotic disease with limited treatment …
tapeworm Echinococcus multilocularis, is a severe zoonotic disease with limited treatment …
Regulation of DNA methylation on key parasitism genes of Cysticercus cellulosae revealed by integrative epigenomic-transcriptomic analyses
X Wang, W Song, G Ji, Y Song, X Liu, X Luo, M Liu… - Hereditas, 2021 - Springer
Background The life cycle of Taenia solium is characterized by different stages of
development, requiring various kinds of hosts that can appropriately harbor the eggs …
development, requiring various kinds of hosts that can appropriately harbor the eggs …