The long and short non-coding RNAs modulating EZH2 signaling in cancer
Non-coding RNAs (ncRNAs) are a large family of RNA molecules with no capability in
encoding proteins. However, they participate in developmental and biological processes …
encoding proteins. However, they participate in developmental and biological processes …
siRNA: Mechanism of action, challenges, and therapeutic approaches
Owing to specific and compelling gene silencing, RNA interference (RNAi) is expected to
become an essential approach in treating a variety of infectious, hemato-oncological …
become an essential approach in treating a variety of infectious, hemato-oncological …
Advances in our understanding of the molecular mechanisms of action of cisplatin in cancer therapy
Cisplatin and other platinum-based chemotherapeutic drugs have been used extensively for
the treatment of human cancers such as bladder, blood, breast, cervical, esophageal, head …
the treatment of human cancers such as bladder, blood, breast, cervical, esophageal, head …
Curcumin and its derivatives in cancer therapy: Potentiating antitumor activity of cisplatin and reducing side effects
Curcumin is a phytochemical isolated from Curcuma longa with potent tumor‐suppressor
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …
activity, which has shown significant efficacy in pre‐clinical and clinical studies. Curcumin …
[HTML][HTML] Long non-coding RNAs and exosomal lncRNAs: Potential functions in lung cancer progression, drug resistance and tumor microenvironment remodeling
Among the different kinds of tumors threatening human life, lung cancer is one that is
commonly observed in both males and females. The aggressive behavior of lung cancer …
commonly observed in both males and females. The aggressive behavior of lung cancer …
NF‐κB as a regulator of cancer metastasis and therapy response: A focus on epithelial–mesenchymal transition
Metastasis of tumor cells is a complex challenge and significantly diminishes the overall
survival and prognosis of cancer patients. The epithelial‐to‐mesenchymal transition (EMT) …
survival and prognosis of cancer patients. The epithelial‐to‐mesenchymal transition (EMT) …
[HTML][HTML] Progress in targeting PTEN/PI3K/Akt axis in glioblastoma therapy: Revisiting molecular interactions
M Hashemi, S Etemad, S Rezaei, S Ziaolhagh… - Biomedicine & …, 2023 - Elsevier
Glioblastoma (GBM) is one of the most malignant cancers of central nervous system and due
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …
to its sensitive location, surgical resection has high risk and therefore, chemotherapy and …
[HTML][HTML] Pre-clinical and clinical importance of miR-21 in human cancers: Tumorigenesis, therapy response, delivery approaches and targeting agents
M Hashemi, MSA Mirdamadi, Y Talebi… - Pharmacological …, 2023 - Elsevier
The field of non-coding RNA (ncRNA) has made significant progress in understanding the
pathogenesis of diseases and has broadened our knowledge towards their targeting …
pathogenesis of diseases and has broadened our knowledge towards their targeting …
[HTML][HTML] LncRNA-miRNA axis in tumor progression and therapy response: An emphasis on molecular interactions and therapeutic interventions
Epigenetic factors are critical regulators of biological and pathological mechanisms and they
could interact with different molecular pathways. Targeting epigenetic factors has been an …
could interact with different molecular pathways. Targeting epigenetic factors has been an …
Ferroptosis: From regulation of lipid peroxidation to the treatment of diseases
Y Lv, M Wu, Z Wang, J Wang - Cell Biology and Toxicology, 2023 - Springer
Ferroptosis is a regulated cell death mainly manifested by iron-dependent lipid peroxide
accumulation. The leading cause of ferroptosis is the imbalance of intracellular oxidative …
accumulation. The leading cause of ferroptosis is the imbalance of intracellular oxidative …