Cancer is the second leading cause of death worldwide and epidemiological projections
predict growing cancer mortality rates in the next decades. Cancer has a close relationship …

Simple Summary This review summarizes the pivotal role of tumor-infiltrating immune cells
(TIICs) within the tumor microenvironment (TME) and their impact on cancer prognosis and …

Saikosaponin A (SSa) is isolated from the dried root of Radix Bupleuri, an herb widely used
in traditional Chinese medicine, exerting antitumor activities. The T helper cell type 1 …

PURPOSE Tumor-infiltrating lymphocytes (TILs) and their spatial characterizations on whole-
slide images (WSIs) of histopathology sections have become crucial in diagnosis, prognosis …

Background Glioma is the most common primary intracranial malignancy in clinical practice,
and in particular, IDH‐wildtype glioblastoma has the worst prognosis. In recent years …

Breast cancer (BC) is a health problem worldwide; there is evidence that inflammatory
cytokines are increased in BC. Macrophage migration inhibitory factor (MIF) has multiple …

Ductal carcinoma in situ (DCIS) encompasses a highly heterogeneous group of lesions that
differ with regard to their clinical presentations, histologic features, biomarker profiles …

Aims Host immunity influences cancer progression and therapeutic response. We
investigated the potential of tumour‐infiltrating lymphocytes (TIL s) around ductal carcinoma …

Understanding cancer mechanisms, defining subtypes, predicting prognosis and assessing
therapy efficacy are crucial aspects of cancer research. Gene-expression signatures derived …

Objectives Since most patients with ductal carcinoma in situ (DCIS) of the breast are treated
upon diagnosis, evidence on its natural progression to invasive carcinoma is limited. It is …