Obesity is defined as excessive body fat accumulation, and worldwide obesity has nearly
tripled since 1975. Excess of free fatty acids (FFAs) and triglycerides in obese individuals …

This article provides an overview of studies addressing effects of ionizing radiation on the
heart. Clinical studies have identified early and late manifestations of radiation-induced …

Magnesium isoglycyrrhizinate (MgIG) is a magnesium salt of the 18-α glycyrrhizic acid
stereoisomer that has exhibited hepato-protective effects and has anti-inflammatory …

Heart failure (HF) is the end stage of many cardiovascular diseases and seriously threatens
people's health. This article aimed to explore the biological role of fat-mass and obesity …

The response to hypoxia is primarily mediated by the hypoxia-inducible transcription factor
(HIF). Levels of HIF are regulated by the oxygen-sensing HIF hydroxylases, members of the …

Genome-wide association studies have uncovered over a 100 genetic loci associated with
atrial fibrillation (AF), the most common arrhythmia. Many of the top AF-associated loci …

Patients with heart failure continue to suffer adverse health consequences despite advances
in therapies over the past 2 decades. Identification of novel therapeutic targets that may …

Despite improvements in the therapy of underlying heart disease, sudden cardiac death is a
major cause of death worldwide. Disturbed Na and Ca handling is known to be a major …

Progress in human genetic and genomic research has led to the identification of genetic
variants associated with specific cardiovascular diseases (CVDs), but the pathogenic …

Aims Heart failure (HF) is a prevalent age‐related cardiovascular disease with poor
prognosis in the elderly population. This study aimed to establish the causal relationship …