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The C. elegans model in toxicity testing
PR Hunt - Journal of Applied Toxicology, 2017 - Wiley Online Library
Caenorhabditis elegans is a small nematode that can be maintained at low cost and
handled using standard in vitro techniques. Unlike toxicity testing using cell cultures, C …
handled using standard in vitro techniques. Unlike toxicity testing using cell cultures, C …
Coding or noncoding, the converging concepts of RNAs
J Li, C Liu - Frontiers in genetics, 2019 - frontiersin.org
Technological advances over the past decade have unraveled the remarkable complexity of
RNA. The identification of small peptides encoded by long non-coding RNAs (lncRNAs) as …
RNA. The identification of small peptides encoded by long non-coding RNAs (lncRNAs) as …
OrthoVenn3: an integrated platform for exploring and visualizing orthologous data across genomes
Advancements in comparative genomics research have led to a growing interest in studying
species evolution and genetic diversity. To facilitate this research, OrthoVenn3 has been …
species evolution and genetic diversity. To facilitate this research, OrthoVenn3 has been …
CAFE 5 models variation in evolutionary rates among gene families
Motivation Genome sequencing projects have revealed frequent gains and losses of genes
between species. Previous versions of our software, Computational Analysis of gene Family …
between species. Previous versions of our software, Computational Analysis of gene Family …
Classification and function of small open reading frames
JP Couso, P Patraquim - Nature reviews Molecular cell biology, 2017 - nature.com
Small open reading frames (smORFs) of 100 codons or fewer are usually—if arbitrarily—
excluded from proteome annotations. Despite this, the genomes of many metazoans …
excluded from proteome annotations. Despite this, the genomes of many metazoans …
Carbonic anhydrases in metazoan model organisms: molecules, mechanisms, and physiology
During the past three decades, mice, zebrafish, fruit flies, and Caenorhabditis elegans have
been the primary model organisms used for the study of various biological phenomena …
been the primary model organisms used for the study of various biological phenomena …
Developmental genetics with model organisms
U Irion, C Nüsslein-Volhard - Proceedings of the National Academy of …, 2022 - pnas.org
In Darwin's and Mendel's times, researchers investigated a wealth of organisms, chosen to
solve particular problems for which they seemed especially well suited. Later, a focus on a …
solve particular problems for which they seemed especially well suited. Later, a focus on a …
Drosophila as an In Vivo Model for Human Neurodegenerative Disease
With the increase in the ageing population, neurodegenerative disease is devastating to
families and poses a huge burden on society. The brain and spinal cord are extraordinarily …
families and poses a huge burden on society. The brain and spinal cord are extraordinarily …
The developmental transcriptome of Drosophila melanogaster
Drosophila melanogaster is one of the most well studied genetic model organisms;
nonetheless, its genome still contains unannotated coding and non-coding genes …
nonetheless, its genome still contains unannotated coding and non-coding genes …
Initial sequencing and analysis of the human genome
US DOE Joint Genome Institute: Hawkins Trevor 4 … - nature, 2001 - nature.com
The human genome holds an extraordinary trove of information about human development,
physiology, medicine and evolution. Here we report the results of an international …
physiology, medicine and evolution. Here we report the results of an international …