[HTML][HTML] An evolutionary perspective of lifespan and epigenetic inheritance

MT Mc Auley - Experimental Gerontology, 2023 - Elsevier
In the last decade epigenetics has come to the fore as a discipline which is central to
biogerontology. Age associated epigenetic changes are routinely linked with pathologies …

DNA methylation in newborns conceived by assisted reproductive technology

SE Håberg, CM Page, Y Lee, HE Nustad… - Nature …, 2022 - nature.com
Assisted reproductive technology (ART) may affect fetal development through epigenetic
mechanisms as the timing of ART procedures coincides with the extensive epigenetic …

Genetic, parental and lifestyle factors influence telomere length

S Andreu-Sánchez, G Aubert… - Communications …, 2022 - nature.com
The average length of telomere repeats (TL) declines with age and is considered to be a
marker of biological ageing. Here, we measured TL in six blood cell types from 1046 …

Associations between nutrients in one-carbon metabolism and fetal DNA methylation in pregnancies with or without gestational diabetes mellitus

I Kadam, M Dalloul, J Hausser, M Huntley… - Clinical …, 2023 - Springer
Background Gestational diabetes mellitus (GDM), characterized by hyperglycemia that
develops during pregnancy, increases the risk of fetal macrosomia, childhood obesity and …

Breastfeeding effects on DNA methylation in the offspring: A systematic literature review

FP Hartwig, C Loret de Mola, NM Davies, CG Victora… - PloS one, 2017 - journals.plos.org
Background Breastfeeding benefits both infants and mothers. Recent research shows long-
term health and human capital benefits among individuals who were breastfed. Epigenetic …

Maternal age and the prevalence of congenital heart defects in Europe, 1995–2015: A register‐based study

C Mamasoula, T Bigirumurame… - Birth defects …, 2023 - Wiley Online Library
Background Evidence on the direction and strength of association between maternal age
and the prevalence of congenital heart defects (CHD) in different age group categories is …

Maternal adverse childhood experiences (ACEs) and DNA methylation of newborns in cord blood

P Collender, AK Bozack, S Veazie… - Clinical …, 2023 - Springer
Abstract Background Adverse childhood experiences (ACEs) increase the risk of poor health
outcomes later in life. Psychosocial stressors may also have intergenerational health effects …

Socioeconomic position during pregnancy and DNA methylation signatures at three stages across early life: epigenome-wide association studies in the ALSPAC birth …

R Alfano, F Guida, B Galobardes… - International journal …, 2019 - academic.oup.com
Background Socioeconomic experiences are recognized determinants of health, and recent
work has shown that social disadvantages in early life may induce sustained biological …

Transtorno do espectro do autismo e idade dos genitores: estudo de caso-controle no Brasil

FA Maia, MTC Almeida, MR Alves… - Cadernos de Saúde …, 2018 - SciELO Brasil
O transtorno do espectro do autismo (TEA) tem se tornado um problema de saúde pública,
com grande impacto familiar, social e econômico. O objetivo deste trabalho foi estimar a …

pwrEWAS: a user-friendly tool for comprehensive power estimation for epigenome wide association studies (EWAS)

S Graw, R Henn, JA Thompson, DC Koestler - BMC bioinformatics, 2019 - Springer
Background When designing an epigenome-wide association study (EWAS) to investigate
the relationship between DNA methylation (DNAm) and some exposure (s) or phenotype (s) …