[HTML][HTML] An evolutionary perspective of lifespan and epigenetic inheritance
MT Mc Auley - Experimental Gerontology, 2023 - Elsevier
In the last decade epigenetics has come to the fore as a discipline which is central to
biogerontology. Age associated epigenetic changes are routinely linked with pathologies …
biogerontology. Age associated epigenetic changes are routinely linked with pathologies …
DNA methylation in newborns conceived by assisted reproductive technology
Assisted reproductive technology (ART) may affect fetal development through epigenetic
mechanisms as the timing of ART procedures coincides with the extensive epigenetic …
mechanisms as the timing of ART procedures coincides with the extensive epigenetic …
Genetic, parental and lifestyle factors influence telomere length
S Andreu-Sánchez, G Aubert… - Communications …, 2022 - nature.com
The average length of telomere repeats (TL) declines with age and is considered to be a
marker of biological ageing. Here, we measured TL in six blood cell types from 1046 …
marker of biological ageing. Here, we measured TL in six blood cell types from 1046 …
Associations between nutrients in one-carbon metabolism and fetal DNA methylation in pregnancies with or without gestational diabetes mellitus
I Kadam, M Dalloul, J Hausser, M Huntley… - Clinical …, 2023 - Springer
Background Gestational diabetes mellitus (GDM), characterized by hyperglycemia that
develops during pregnancy, increases the risk of fetal macrosomia, childhood obesity and …
develops during pregnancy, increases the risk of fetal macrosomia, childhood obesity and …
Breastfeeding effects on DNA methylation in the offspring: A systematic literature review
Background Breastfeeding benefits both infants and mothers. Recent research shows long-
term health and human capital benefits among individuals who were breastfed. Epigenetic …
term health and human capital benefits among individuals who were breastfed. Epigenetic …
Maternal age and the prevalence of congenital heart defects in Europe, 1995–2015: A register‐based study
C Mamasoula, T Bigirumurame… - Birth defects …, 2023 - Wiley Online Library
Background Evidence on the direction and strength of association between maternal age
and the prevalence of congenital heart defects (CHD) in different age group categories is …
and the prevalence of congenital heart defects (CHD) in different age group categories is …
Maternal adverse childhood experiences (ACEs) and DNA methylation of newborns in cord blood
P Collender, AK Bozack, S Veazie… - Clinical …, 2023 - Springer
Abstract Background Adverse childhood experiences (ACEs) increase the risk of poor health
outcomes later in life. Psychosocial stressors may also have intergenerational health effects …
outcomes later in life. Psychosocial stressors may also have intergenerational health effects …
Socioeconomic position during pregnancy and DNA methylation signatures at three stages across early life: epigenome-wide association studies in the ALSPAC birth …
Background Socioeconomic experiences are recognized determinants of health, and recent
work has shown that social disadvantages in early life may induce sustained biological …
work has shown that social disadvantages in early life may induce sustained biological …
Transtorno do espectro do autismo e idade dos genitores: estudo de caso-controle no Brasil
FA Maia, MTC Almeida, MR Alves… - Cadernos de Saúde …, 2018 - SciELO Brasil
O transtorno do espectro do autismo (TEA) tem se tornado um problema de saúde pública,
com grande impacto familiar, social e econômico. O objetivo deste trabalho foi estimar a …
com grande impacto familiar, social e econômico. O objetivo deste trabalho foi estimar a …
pwrEWAS: a user-friendly tool for comprehensive power estimation for epigenome wide association studies (EWAS)
Background When designing an epigenome-wide association study (EWAS) to investigate
the relationship between DNA methylation (DNAm) and some exposure (s) or phenotype (s) …
the relationship between DNA methylation (DNAm) and some exposure (s) or phenotype (s) …