Trauma-induced coagulopathy
Uncontrolled haemorrhage is a major preventable cause of death in patients with traumatic
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …
injury. Trauma-induced coagulopathy (TIC) describes abnormal coagulation processes that …
Review of current transfusion therapy and blood banking practices
Transfusion Medicine is a dynamically evolving field. Recent high-quality research has
reshaped the paradigms guiding blood transfusion. As increasing evidence supports the …
reshaped the paradigms guiding blood transfusion. As increasing evidence supports the …
The European guideline on management of major bleeding and coagulopathy following trauma
DR Spahn, B Bouillon, V Cerny, J Duranteau… - Critical care, 2019 - Springer
Background Severe traumatic injury continues to present challenges to healthcare systems
around the world, and post-traumatic bleeding remains a leading cause of potentially …
around the world, and post-traumatic bleeding remains a leading cause of potentially …
Early and empirical high-dose cryoprecipitate for hemorrhage after traumatic injury: the CRYOSTAT-2 randomized clinical trial
Importance Critical bleeding is associated with a high mortality rate in patients with trauma.
Hemorrhage is exacerbated by a complex derangement of coagulation, including an acute …
Hemorrhage is exacerbated by a complex derangement of coagulation, including an acute …
Effect of fibrinogen concentrate vs cryoprecipitate on blood component transfusion after cardiac surgery: the FIBRES randomized clinical trial
Importance Excessive bleeding is a common complication of cardiac surgery. An important
cause of bleeding is acquired hypofibrinogenemia (fibrinogen level< 1.5-2.0 g/L), for which …
cause of bleeding is acquired hypofibrinogenemia (fibrinogen level< 1.5-2.0 g/L), for which …
Damage control resuscitation in adult trauma patients: what you need to know
DT Lammers, JB Holcomb - Journal of Trauma and Acute Care …, 2023 - journals.lww.com
Death after injury is a worldwide epidemic. Hemorrhage as a cause of death represents the
leading potentially preventable condition. Based on hard-won experience from the recent …
leading potentially preventable condition. Based on hard-won experience from the recent …
Disseminated intravascular coagulation: the past, present, and future considerations
Disseminated intravascular coagulation (DIC) has been understood as a consumptive
coagulopathy. However, impaired hemostasis is a component of DIC that occurs in a …
coagulopathy. However, impaired hemostasis is a component of DIC that occurs in a …
Defining trauma‐induced coagulopathy with respect to future implications for patient management: communication from the SSC of the ISTH
Trauma-induced coagulopathy (TIC) is a clinical scenario spanning the spectrum of
hypocoagulability to hypercoagulability causing a wide range of complications including …
hypocoagulability to hypercoagulability causing a wide range of complications including …
The pathophysiology and management of hemorrhagic shock in the polytrauma patient
A Fecher, A Stimpson, L Ferrigno… - Journal of clinical …, 2021 - mdpi.com
The recognition and management of life-threatening hemorrhage in the polytrauma patient
poses several challenges to prehospital rescue personnel and hospital providers. First …
poses several challenges to prehospital rescue personnel and hospital providers. First …
Point-of-care, goal-directed management of bleeding in trauma patients
POC SCTs are not able to characterise the complexity of trauma-associated coagulopathy.
VETs provide a rapid estimation of underlying haemostatic disorders, thereby providing …
VETs provide a rapid estimation of underlying haemostatic disorders, thereby providing …