Flavones: An important scaffold for medicinal chemistry

M Singh, M Kaur, O Silakari - European journal of medicinal chemistry, 2014 - Elsevier
Flavones have antioxidant, anti-proliferative, anti-tumor, anti-microbial, estrogenic, acetyl
cholinesterase, anti-inflammatory activities and are also used in cancer, cardiovascular …

Antioxidant and prooxidant properties of flavonoids

D Procházková, I Boušová, N Wilhelmová - Fitoterapia, 2011 - Elsevier
The interest in possible health benefits of flavonoids has increased owing to their potent
antioxidant and free radical scavenging activities observed in vitro. Nevertheless, the …

Medicinal plants, human health and biodiversity: a broad review

T Sen, SK Samanta - Biotechnological applications of biodiversity, 2015 - Springer
<? xm-replace_text {Heading}?> Abstract Biodiversity contributes significantly towards
human livelihood and development and thus plays a predominant role in the well being of …

Anti-inflammation activity of flavones and their structure–activity relationship

X Wang, Y Cao, S Chen, J Lin, J Bian… - Journal of Agricultural …, 2021 - ACS Publications
Flavones are an important class of bioactive constituents in foods, and their structural
diversity enables them to interact with different targets. In particular, flavones are known for …

Phenolic compounds as antidiabetic, anti‐inflammatory, and anticancer agents and improvement of their bioavailability by liposomes

VB Tatipamula, B Kukavica - Cell biochemistry and function, 2021 - Wiley Online Library
Phenolic compounds, widespread in plants, are a necessary part of the human regimen due
to their antioxidant and pro‐oxidative properties. Naturally, phenolics structurally range from …

Synthesis of novel pyrazolic analogues of chalcones and their 3-aryl-4-(3-aryl-4, 5-dihydro-1H-pyrazol-5-yl)-1-phenyl-1H-pyrazole derivatives as potential antitumor …

B Insuasty, A Tigreros, F Orozco, J Quiroga… - Bioorganic & medicinal …, 2010 - Elsevier
Novel (E)-1-aryl-3-(3-aryl-1-phenyl-1H-pyrazol-4-yl) prop-2-en-1-ones 5/6 (pyrazolic
chalcones) were synthesized from a Claisen–Schmidt reaction of 3-aryl-1-phenylpyrazol-4 …