The field of chemical senses has made major progress in understanding the cellular
mechanisms of olfaction and taste in the past 2 decades. However, the molecular …

Humans have 396 unique, intact olfactory receptors (ORs), G-protein coupled receptors
(GPCRs) containing receptor-specific binding sites; other mammals have more. Activation of …

One key to animal survival is the detection and avoidance of potentially harmful compounds
by their bitter taste. Variable numbers of taste 2 receptor genes expressed in the gustatory …

The oriental fruit fly Bactrocera dorsalis (Hendel) is a notorious pest of fruit crops. Gravid
females locate suitable oviposition sites by detecting host plant volatiles. Here, we …

G protein-coupled receptors (GPCRs) conserve common structural folds and activation
mechanisms, yet their ligand spectra and functions are highly diverse. This work …

Several studies have demonstrated the expression of odorant receptors (OR) in various
human tissues and their involvement in different physiological and pathophysiological …

Olfactory systems have evolved the extraordinary capability to detect and discriminate
volatile odorous molecules (odorants) in the environment. Fundamentally, this process relies …

The sense of smell helps us navigate the environment, but its molecular architecture and
underlying logic remain understudied. The spatial location of odorant receptor genes (Olfrs) …

Advances in theoretical understanding are frequently unlocked by access to large, diverse
experimental datasets. Our understanding of olfactory neuroscience and psychophysics …

In the present paper, statistical physics formalism was used to understand the olfactory
perception via the investigation of dose-olfactory response curves of a putative adsorption …