The role of astrocyte‐mediated plasticity in neural circuit development and function

NA Perez-Catalan, CQ Doe, SD Ackerman - Neural development, 2021 - Springer
Neuronal networks are capable of undergoing rapid structural and functional changes called
plasticity, which are essential for sha** circuit function during nervous system …

Aberrant calcium signals in reactive astrocytes: a key process in neurological disorders

E Shigetomi, K Saito, F Sano, S Koizumi - International journal of …, 2019 - mdpi.com
Astrocytes are abundant cells in the brain that regulate multiple aspects of neural tissue
homeostasis by providing structural and metabolic support to neurons, maintaining synaptic …

Cortical astrocytes modulate dominance behavior in male mice by regulating synaptic excitatory and inhibitory balance

K Noh, WH Cho, BH Lee, DW Kim, YS Kim, K Park… - Nature …, 2023 - nature.com
Social hierarchy is established as an outcome of individual social behaviors, such as
dominance behavior during long-term interactions with others. Astrocytes are implicated in …

Astrocytes close the mouse critical period for visual plasticity

J Ribot, R Breton, CF Calvo, J Moulard, P Ezan… - Science, 2021 - science.org
Brain postnatal development is characterized by critical periods of experience-dependent
remodeling of neuronal circuits. Failure to end these periods results in neurodevelopmental …

Astrocyte-secreted IL-33 mediates homeostatic synaptic plasticity in the adult hippocampus

Y Wang, WY Fu, K Cheung, KW Hung… - Proceedings of the …, 2021 - National Acad Sciences
Hippocampal synaptic plasticity is important for learning and memory formation.
Homeostatic synaptic plasticity is a specific form of synaptic plasticity that is induced upon …

The specific role of reactive astrocytes in stroke

L Li, J Zhou, L Han, X Wu, Y Shi, W Cui… - Frontiers in Cellular …, 2022 - frontiersin.org
Astrocytes are essential in maintaining normal brain functions such as blood brain barrier
(BBB) homeostasis and synapse formation as the most abundant cell type in the central …

Learning-associated astrocyte ensembles regulate memory recall

MR Williamson, W Kwon, J Woo, Y Ko, E Maleki, K Yu… - Nature, 2024 - nature.com
The physical manifestations of memory formation and recall are fundamental questions that
remain unresolved. At the cellular level, ensembles of neurons called engrams are activated …

Microglia control glutamatergic synapses in the adult mouse hippocampus

B Basilico, L Ferrucci, P Ratano, MT Golia, A Grimaldi… - Glia, 2022 - Wiley Online Library
Microglia cells are active players in regulating synaptic development and plasticity in the
brain. However, how they influence the normal functioning of synapses is largely unknown …

Elimination of the four extracellular matrix molecules tenascin-C, tenascin-R, brevican and neurocan alters the ratio of excitatory and inhibitory synapses

C Gottschling, D Wegrzyn, B Denecke, A Faissner - Scientific reports, 2019 - nature.com
The synaptic transmission in the mammalian brain is not limited to the interplay between the
pre-and the postsynapse of neurons, but involves also astrocytes as well as extracellular …

Multiple forms of working memory emerge from synapse–astrocyte interactions in a neuron–glia network model

M De Pittà, N Brunel - … of the National Academy of Sciences, 2022 - National Acad Sciences
Persistent activity in populations of neurons, time-varying activity across a neural population,
or activity-silent mechanisms carried out by hidden internal states of the neural population …