Mycobacteriophages—bacteriophages infecting Mycobacterium hosts—contribute
substantially to our understanding of viral diversity and evolution, provide resources for …

Antimicrobial resistance is an increasing threat to human populations. The emergence of
multidrug-resistant “superbugs” in mycobacterial infections has further complicated the …

Mycobacterium tuberculosis (Mtb) encodes five type VII secretion systems (T7SS),
designated ESX-1–ESX-5, that are critical for growth and pathogenesis. The best …

Despite many methodological advances that have facilitated investigation of Mycobacterium
tuberculosis pathogenesis, analysis of essential gene function in this slow-growing …

Increasing antimicrobial resistance compels the search for next-generation inhibitors with
differing or multiple molecular targets. In this regard, energy conservation in Mycobacterium …

The resilience of Mycobacterium tuberculosis (MTB) emerges from its ability to effectively
counteract immunological, environmental and antitubercular challenges. Here, we …

The global epidemic of tuberculosis (TB) imposes a sustained epidemiologic vigilance and
investments in research by governments. Mycobacterium tuberculosis, the main causative …

A collection of over 1600 sequenced bacteriophages isolated on a single host strain,
Mycobacterium smegmatis mc 2 155, can be grouped into over two dozen types that have …

Mycobacterium abscessus causes severe disease in patients with cystic fibrosis. Little is
known in M. abscessus about the roles of small regulatory RNAs (sRNA) in gene regulation …

Iron is an essential element for life, but its soluble form is scarce in the environment and is
rarer in the human body. Mtb (Mycobacterium tuberculosis) produces two aryl-capped …