Of the various methods available for high‐performance liquid chromatography separation of
enantiomers (of eg amino acids and amino group containing compounds) by the pre …

Profiles of Drug Substances, Excipients, and Related Methodology, Volume 45, presents
comprehensive reviews of drug substances and additional materials, with critical review …

β-adrenergic antagonists (β-blockers) with at least one chiral center are an exceedingly
important class of drugs used mostly to treat cardiovascular diseases. At least 70 β-blockers …

Propranolol is a noncardioselective β-blocker. It is reported to have membrane-stabilizing
properties, but it does not own intrinsic sympathomimetic activity. Propranolol hydrochloride …

Diastereomers of (RS)‐propranolol were synthesized using (S)‐levofloxacin‐based new
chiral derivatizing reagents (CDRs). Levofloxacin was chosen as the pure (S)‐enantiomer …

An efficient and concise approach for recognizing chirality and determining the absolute
configuration of the diastereomers of (RS)-Betaxolol,[(RS)-Bet] is described, which in turn is …

Propranolol, a β‐adrenergic receptor antagonist, is a chiral compound that is marketed as a
racemate, but only the (S)‐(−)‐enantiomer is responsible for the β‐adrenoceptor blocking …

Enantioseparation of a few commonly administered racemic β‐adrenolytics (namely,
carvedilol, betaxolol, salbutamol and bisoprolol) has been achieved using a water micellar …

The de‐novo approach of mixing chirally pure reagents or Cu (II)‐L‐amino acid complexes
in the slurry of silica gel for preparing TLC plates was reported from author's laboratory and …

Diastereomers of racemic β‐adrenolytic drugs [namely (RS)‐propranolol,(RS)‐metoprolol
and (RS)‐atenolol] were synthesized under microwave irradiation with (S)‐ketoprofen based …