Extracellular HtrA serine proteases: an emerging new strategy in bacterial pathogenesis
S Backert, S Bernegger, J Skórko‐Glonek… - Cellular …, 2018 - Wiley Online Library
The HtrA family of chaperones and serine proteases is important for regulating stress
responses and controlling protein quality in the periplasm of bacteria. HtrA is also …
responses and controlling protein quality in the periplasm of bacteria. HtrA is also …
Extracellular vesicles with possible roles in gut intestinal tract homeostasis and IBD
X Chang, SL Wang, SB Zhao, YH Shi… - Mediators of …, 2020 - Wiley Online Library
The intestinal tract consists of various types of cells, such as epithelial cells, Paneth cells,
macrophages, and lymphocytes, which constitute the intestinal immune system and play a …
macrophages, and lymphocytes, which constitute the intestinal immune system and play a …
Campylobacter jejuni Surface-Bound Protease HtrA, but Not the Secreted Protease nor Protease in Shed Membrane Vesicles, Disrupts Epithelial Cell-to-Cell …
I Sharafutdinov, N Tegtmeyer, M Rohde, A Olofsson… - Cells, 2024 - mdpi.com
Fundamental functions of the intestinal epithelium include the digestion of food, absorption
of nutrients, and its ability to act as the first barrier against intruding microbes …
of nutrients, and its ability to act as the first barrier against intruding microbes …
Trimer stability of Helicobacter pylori HtrA is regulated by a natural mutation in the protease domain
U Zarzecka, N Tegtmeyer, H Sticht… - Medical Microbiology and …, 2023 - Springer
The human pathogen Helicobacter pylori is a major risk factor for gastric disease
development. Serine protease HtrA is an important bacterial virulence factor that cleaves the …
development. Serine protease HtrA is an important bacterial virulence factor that cleaves the …
[HTML][HTML] The role played by bacterial infections in the onset and metastasis of cancer
Understanding various responses of cells towards change in their external environment,
presence of other species and is important in identifying and correlating the mechanisms …
presence of other species and is important in identifying and correlating the mechanisms …
[HTML][HTML] Molecular structures mediating adhesion of Campylobacter jejuni to abiotic and biotic surfaces
Abstract Microaerophilic, Gram-negative Campylobacter jejuni is the causative agent of
campylobacteriosis, the most common bacterial gastrointestinal infection worldwide …
campylobacteriosis, the most common bacterial gastrointestinal infection worldwide …
Function of serine protease HtrA in the lifecycle of the foodborne pathogen Campylobacter jejuni
M Boehm, D Simson, U Escher, AM Schmidt… - European Journal of …, 2018 - akjournals.com
Campylobacter jejuni is a major food-borne zoonotic pathogen, responsible for a large
proportion of bacterial gastroenteritis cases, as well as Guillian-Barré and Miller-Fisher …
proportion of bacterial gastroenteritis cases, as well as Guillian-Barré and Miller-Fisher …
Environment Controls LEE Regulation in Enteropathogenic Escherichia coli
A Platenkamp, JL Mellies - Frontiers in microbiology, 2018 - frontiersin.org
Enteropathogenic Escherichia coli (EPEC) is a significant cause of infant morbidity and
mortality in develo** regions of the world. Horizontally acquired genetic elements encode …
mortality in develo** regions of the world. Horizontally acquired genetic elements encode …
Overexpression of serine protease HtrA enhances disruption of adherens junctions, paracellular transmigration and type IV secretion of CagA by Helicobacter pylori
A Harrer, M Boehm, S Backert, N Tegtmeyer - Gut pathogens, 2017 - Springer
Abstract Background The serine protease HtrA is an important factor for regulating stress
responses and protein quality control in bacteria. In recent studies, we have demonstrated …
responses and protein quality control in bacteria. In recent studies, we have demonstrated …
Host cell-surface proteins as substrates of gingipains, the main proteases of Porphyromonas gingivalis
K Hočevar, J Potempa, B Turk - Biological chemistry, 2018 - degruyter.com
Gingipains are extracellular cysteine proteases of the oral pathogen Porphyromonas
gingivalis and are its most potent virulence factors. They can degrade a great variety of host …
gingivalis and are its most potent virulence factors. They can degrade a great variety of host …