The long-term use of proton pump inhibitors (PPIs) can lead to increased gastric pH,
hypochlorhydria and in some cases to achlorhydria when compared to other acid …

COX2-selective and nonselective (ns) nonsteroidal anti-inflammatory drugs (NSAIDs) are
widely used for chronic pain management. There are marked differences in the risk of …

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Background: This study's objective was to evaluate the association between protonpump
inhibitor (PPI) use and bone fracture incidence and bone mineral density (BMD) by meta …

Understanding and predicting the mechanical behavior of myocardium under healthy and
pathophysiological conditions are vital to develo** novel cardiac therapies and promoting …

Objective: We aimed at summarizing current evidence about mechanisms for potentially
harmful effects of Proton Pump Inhibitors (PPIs). Methods: A Pubmed search was performed …

Abstract Objectives In the United States, proton pump inhibitors (PPIs) are one of the most
commonly prescribed classes of drugs, but contemporary data on national-level utilization …

Background The purpose of this study was to review the current management of gastro-
oesophageal reflux disease (GORD), including treatment costs, safety profile and …

Background Although randomized controlled trials (RCTs) have suggested a non-significant
increased risk of stroke among proton pump inhibitor (PPI) users, the association has not …

Proton pump inhibitors (PPIs) are widely used drugs that may increase the cardiovascular
risk by mechanisms not entirely known. While PPIs increase asymmetric dimethylarginine …