Circulating biomarkers in patients with glioblastoma

J Müller Bark, A Kulasinghe, B Chua, BW Day… - British journal of …, 2020 - nature.com
Gliomas are the most common tumours of the central nervous system and the most
aggressive form is glioblastoma (GBM). Despite advances in treatment, patient survival …

How to differentiate pseudoprogression from true progression in cancer patients treated with immunotherapy

Y Ma, Q Wang, Q Dong, L Zhan… - American journal of …, 2019 - pmc.ncbi.nlm.nih.gov
Immunotherapy has achieved unprecedented clinical efficacy in patients with various types
of advanced tumors; however, some patients experience delayed tumor shrinkage following …

Incorporating diffusion-and perfusion-weighted MRI into a radiomics model improves diagnostic performance for pseudoprogression in glioblastoma patients

JY Kim, JE Park, Y Jo, WH Shim, SJ Nam… - Neuro …, 2019 - academic.oup.com
Background Pseudoprogression is a diagnostic challenge in early posttreatment
glioblastoma. We therefore developed and validated a radiomics model using …

[HTML][HTML] Liquid biopsy in glioblastoma

L Ronvaux, M Riva, A Coosemans, M Herzog… - Cancers, 2022 - mdpi.com
Simple Summary Glioblastoma is the most common and malignant primary brain tumor.
Despite intensive research for new treatments, the survival of patients has not significantly …

Assessment and prediction of glioblastoma therapy response: challenges and opportunities

D Qi, J Li, CC Quarles, E Fonkem, E Wu - Brain, 2023 - academic.oup.com
Glioblastoma is the most aggressive type of primary adult brain tumour. The median survival
of patients with glioblastoma remains approximately 15 months, and the 5-year survival rate …

Perfusion MRI in treatment evaluation of glioblastomas: Clinical relevance of current and future techniques

BRJ van Dijken, PJ van Laar, M Smits… - Journal of Magnetic …, 2019 - Wiley Online Library
Treatment evaluation of patients with glioblastomas is important to aid in clinical decisions.
Conventional MRI with contrast is currently the standard method, but unable to differentiate …

[HTML][HTML] Towards immunotherapy for pediatric brain tumors

SS Wang, P Bandopadhayay, MR Jenkins - Trends in immunology, 2019 - cell.com
Pediatric brain tumors are the leading cause of childhood cancer-related death.
Immunotherapy is a powerful new approach for treating some refractory cancers; applying …

[HTML][HTML] Machine learning and glioma imaging biomarkers

TC Booth, M Williams, A Luis, J Cardoso, K Ashkan… - Clinical radiology, 2020 - Elsevier
AIM To review how machine learning (ML) is applied to imaging biomarkers in neuro-
oncology, in particular for diagnosis, prognosis, and treatment response monitoring …

Circulating liquid biopsy biomarkers in Glioblastoma: advances and challenges

AA Seyhan - International Journal of Molecular Sciences, 2024 - pmc.ncbi.nlm.nih.gov
Gliomas, particularly glioblastoma (GBM), represent the most prevalent and aggressive
tumors of the central nervous system (CNS). Despite recent treatment advancements, patient …

Interferon regulatory factor 9 structure and regulation

A Paul, TH Tang, SK Ng - Frontiers in immunology, 2018 - frontiersin.org
Interferon regulatory factor 9 (IRF9) is an integral transcription factor in mediating the type I
interferon antiviral response, as part of the interferon-stimulated gene factor 3. However, the …