Role of Hydrogen Sulfide in Oncological and Non-oncological disorders and its regulation by non-coding RNAs: a Comprehensive Review

RA Youness, DA Habashy, N Khater, K Elsayed… - Non-coding RNA, 2024 - mdpi.com
Recently, myriad studies have defined the versatile abilities of gasotransmitters and their
synthesizing enzymes to play a “Maestro” role in orchestrating several oncological and non …

Role of hydrogen sulfide in health and disease

YQ **, H Yuan, YF Liu, YW Zhu, Y Wang… - MedComm, 2024 - Wiley Online Library
In the past, hydrogen sulfide (H2S) was recognized as a toxic and dangerous gas; in recent
years, with increased research, we have discovered that H2S can act as an endogenous …

M6A-methylated circPOLR2B forms an R-loop and regulates the biological behavior of glioma stem cells through positive feedback loops

H Lin, Z Cui, TE, H Xu, D Wang, P Wang, X Ruan… - Cell Death & …, 2024 - nature.com
Glioma is the most common primary brain tumor, and targeting glioma stem cells (GSCs) has
become a key aspect of glioma treatment. In this study, we discovered a molecular network …

Should I stay or should I go? Transsulfuration influences invasion and growth in glioblastoma

AK Ponti, DJ Silver, C Hine… - The Journal of Clinical …, 2024 - Am Soc Clin Investig
A major challenge in treating patients with glioblastoma is the inability to eliminate highly
invasive cells with chemotherapy, radiation, or surgical resection. As cancer cells face the …

Exploring the impact of hydrogen sulfide on hematologic malignancies: A review

S Lou, ZL Jiang, YW Zhu, RY Zhang, Y Wang, T Chu… - Cellular …, 2024 - Elsevier
Hydrogen sulfide (H 2 S) is one of the three most crucial gaseous messengers in the body.
The discovery of H 2 S donors, coupled with its endogenous synthesis capability, has …

Detection of polymorphisms in six genes and their association analysis with litter size in sheep

K Liu, Y Liu, M Chu - Animal Biotechnology, 2024 - Taylor & Francis
Litter size in sheep is a complex trait controlled by micro-effective polygenes. APAF1,
CLSTN2, CTH, PLCB1, PLCB4, and CHST11 are all involved in mammalian reproduction …

[HTML][HTML] Allicin in pregnancy diets modulates steroid metabolism in pregnant sows and placental sulphate metabolism promoting placental angiogenesis and foetal …

J Peng, Y Zhang, Q Liu, Y Tang, W Zhang, S Zheng… - animal, 2024 - Elsevier
The low-birth-weight of piglets is an important factor affecting pig enterprises. The placenta,
as a key organ for material exchange between mother and foetus, directly influences the …

H2S donor GYY4137 mitigates sFlt-1-induced hypertension and vascular dysfunction in pregnant rats

P Yadav, JS Mishra, MW Hurt, DB Chen… - Biology of …, 2024 - academic.oup.com
Gestational hypertension, often associated with elevated soluble Fms-related receptor
tyrosine kinase 1 (sFlt-1), poses significant risks to both maternal and fetal health. Hydrogen …

[HTML][HTML] PSMC2 promotes glioma progression by regulating immune microenvironment and PI3K/AKT/mTOR pathway

Y Wang, S Zhang, Z Zhao, Q **, Z Wang, Z Song, L Liu… - Immunobiology, 2024 - Elsevier
Background Glioma, the most frequent and malignant central nervous system (CNS) cancer,
has a bad outcome. Proteasome 26S subunit ATPase 2 (PSMC2) is an essential part of the …

Hydrogen Sulfide Promotes TAM‐M1 Polarization through Activating IRE‐1α Pathway via GRP78 S‐Sulfhydrylation to against Breast Cancer

M Ju, W Tong, J Bi, X Zeng, A Qi, M Sun, J Wen… - Advanced … - Wiley Online Library
Abstract Hydrogen sulfide (H2S)‐mediated protein S‐sulfhydration has been shown to play
critical roles in several diseases. Tumor‐associated macrophages (TAMs) are the …