Charged particle therapy—optimization, challenges and future directions

JS Loeffler, M Durante - Nature reviews Clinical oncology, 2013 - nature.com
The use of charged particle therapy to control tumours non-invasively offers advantages
over conventional radiotherapy. Protons and heavy ions deposit energy far more selectively …

“Radiobiology of Proton Therapy”: Results of an international expert workshop

A Lühr, C von Neubeck, J Pawelke, A Seidlitz… - Radiotherapy and …, 2018 - Elsevier
The physical properties of proton beams offer the potential to reduce toxicity in tumor-
adjacent normal tissues. Toward this end, the number of proton radiotherapy facilities has …

Proton versus intensity-modulated radiotherapy for prostate cancer: patterns of care and early toxicity

JB Yu, PR Soulos, J Herrin, LD Cramer… - Journal of the …, 2013 - academic.oup.com
Background Proton radiotherapy (PRT) is an emerging treatment for prostate cancer despite
limited knowledge of clinical benefit or potential harms compared with other types of …

Investigating deformable image registration and scatter correction for CBCT‐based dose calculation in adaptive IMPT

C Kurz, F Kamp, YK Park, C Zöllner, S Rit… - Medical …, 2016 - Wiley Online Library
Purpose This work aims at investigating intensity corrected cone‐beam x‐ray computed
tomography (CBCT) images for accurate dose calculation in adaptive intensity modulated …

Comparative toxicities and cost of intensity-modulated radiotherapy, proton radiation, and stereotactic body radiotherapy among younger men with prostate cancer

HY Pan, J Jiang, KE Hoffman, C Tang… - Journal of Clinical …, 2018 - ascopubs.org
Purpose To compare the toxicities and cost of proton radiation and stereotactic body
radiotherapy (SBRT) with intensity-modulated radiotherapy (IMRT) for prostate cancer …

[HTML][HTML] Five-year biochemical results, toxicity, and patient-reported quality of life after delivery of dose-escalated image guided proton therapy for prostate cancer

C Bryant, TL Smith, RH Henderson, BS Hoppe… - International Journal of …, 2016 - Elsevier
Purpose To report clinical outcomes in patients treated with image guided proton therapy
(PT) for localized prostate cancer. Methods and Materials The medical records of 1327 men …

High-risk prostate cancer: from definition to contemporary management

PJ Bastian, SA Boorjian, A Bossi, A Briganti… - European urology, 2012 - Elsevier
CONTEXT: High-risk prostate cancer (PCa) is a potentially lethal disease. It is clinically
important to identify patients with high-risk PCa early on because they stand to benefit the …

Treatment planning comparison of IMPT, VMAT and 4π radiotherapy for prostate cases

A Tran, J Zhang, K Woods, V Yu, D Nguyen… - Radiation …, 2017 - Springer
Background Intensity-modulated proton therapy (IMPT), non-coplanar 4π intensity-
modulated radiation therapy (IMRT), and volumetric-modulated arc therapy (VMAT) …

Five-year outcomes from 3 prospective trials of image-guided proton therapy for prostate cancer

NP Mendenhall, BS Hoppe, RC Nichols… - International Journal of …, 2014 - Elsevier
Purpose To report 5-year clinical outcomes of 3 prospective trials of image-guided proton
therapy for prostate cancer. Methods and Materials A total of 211 prostate cancer patients …

Risk of secondary malignant neoplasms from proton therapy and intensity-modulated x-ray therapy for early-stage prostate cancer

JD Fontenot, AK Lee, WD Newhauser - International Journal of Radiation …, 2009 - Elsevier
PURPOSE: To assess the risk of a secondary malignant neoplasm (SMN) from proton
therapy relative to intensity-modulated radiation therapy (IMRT) using X-rays, taking into …