Genome-wide association studies (GWAS) involve testing genetic variants across the
genomes of many individuals to identify genotype–phenotype associations. GWAS have …

Gestational diabetes mellitus (GDM) traditionally refers to abnormal glucose tolerance with
onset or first recognition during pregnancy. GDM has long been associated with obstetric …

Obesity is among the most threatening health burdens worldwide and its prevalence has
markedly increased over the last decades. Obesity maybe considered a heritable trait …

In high-, middle-and low-income countries, the rising prevalence of obesity is the underlying
cause of numerous health complications and increased mortality. Being a complex and …

Gestational diabetes mellitus (GDM) is a common metabolic disorder affecting more than 16
million pregnancies annually worldwide,. GDM is related to an increased lifetime risk of type …

Single nucleotide polymorphisms (SNPs) that cluster in the first intron of fat mass and
obesity associated (FTO) gene are associated obesity traits in genome-wide association …

Obesity and its related health complications is a major problem worldwide. Hypothalamus
and their signalling molecules play a critical role in the intervening and coordination with …

Background Obesity poses significant challenges to healthcare globally, particularly through
its bi‐directional relationship with co‐morbid metabolic conditions such as type 2 diabetes …

The global rise in the prevalence of obesity and associated co-morbidities such as type 2
diabetes, cardiovascular disease, and cancer represents a major public health concern. The …

The mammalian proprotein convertases constitute a family of nine secretory serine
proteases that are related to bacterial subtilisin and yeast kexin. Seven of these (proprotein …