Stress-linked psychiatric disorders, including anxiety and major depressive disorder, are
associated with systemic inflammation. Recent studies have reported stress-induced …

This review aims to synthesise a large pre-clinical and clinical literature related to a
hypothesised role of the locus coeruleus norepinephrine system in responses to acute and …

Sleep has a complex micro-architecture, encompassing micro-arousals, sleep spindles and
transitions between sleep stages. Fragmented sleep impairs memory consolidation …

Preclinical and some clinical studies suggest a relationship between perturbation in
magnesium (Mg2+) homeostasis and pathological anxiety, although the underlying …

The main objectives of this study were to investigate the dynamics of the cortisol stress
response and the underlying molecular regulation in adult zebrafish exposed to acute and …

The endocannabinoid system is a widely distributed, neuromodulatory system which serves
an integral role in regulating synaptic transmission. The presence of this system in stress …

Sleep is a crucial biological process that is regulated through complex interactions between
multiple brain regions and neuromodulators. As sleep disorders can have deleterious …

Psychological stressors have a prominent effect on sleep in general, and rapid eye
movement (REM) sleep in particular. Disruptions in sleep are a prominent feature, and …

Stress, a prevalent experience in modern society, is a major risk factor for many psychiatric
disorders. Although sensorimotor abnormalities are often present in these disorders, little is …

Granule cells (GCs) of the cerebellar input layer express high-affinity δ GABA A subunit-
containing GABA A receptors (δGABA A Rs) that respond to ambient GABA levels and …