The tumour immune microenvironment is shaped by the crosstalk between cancer cells,
immune cells, fibroblasts, endothelial cells and other stromal components. Although the …

Adjuvants play pivotal roles in vaccine development, enhancing immunization efficacy
through prolonged retention and sustained release of antigen, lymph node targeting, and …

Humanized mice are limited in terms of modeling human immunity, particularly with regards
to antibody responses. Here we constructed a humanized (THX) mouse by grafting non-γ …

The development of preventive and therapeutic vaccines has played a crucial role in
preventing infections and treating chronic and non-communicable diseases, respectively …

Melanoma incidence and mortality rates are historically higher for men than women.
Although emerging studies have highlighted tumorigenic roles for the male sex hormone …

Globally, the majority of people living with HIV are women or girls, but they have been a
minority of participants in clinical trials and observational studies of HIV. Despite this …

As the soil of life, the composition and sha** process of the immune microenvironment of
the uterus is worth exploring. Macrophages, indispensable constituents of the innate …

The effect of sex on the prevalence and severity of parasitic diseases is an emerging area of
research. Several factors underlie sex-based differences, including sociocultural influences …

Men are at higher risk for develo** severe COVID-19 than women, while women are at
higher risk for develo** post-acute sequelae of COVID-19 (PASC). This highlights the …

There are differences in the prevalence of inflammatory diseases between the sexes (sexual
dimorphism), but the underlying mechanisms that regulate tissue immunity remain unclear …