Microbiota-mediated colonization resistance: mechanisms and regulation

G Caballero-Flores, JM Pickard, G Núñez - Nature Reviews …, 2023‏ - nature.com
A dense and diverse microbial community inhabits the gut and many epithelial surfaces.
Referred to as the microbiota, it co-evolved with the host and is beneficial for many host …

The human symbiont Mucispirillum schaedleri: causality in health and disease

S Herp, AC Durai Raj, M Salvado Silva… - Medical microbiology …, 2021‏ - Springer
Trillions of bacteria inhabit the mammalian gastrointestinal tract. In the majority of hosts,
these symbionts contribute largely to beneficial functions promoting microbe-host …

Unravelling the collateral damage of antibiotics on gut bacteria

L Maier, CV Goemans, J Wirbel, M Kuhn, C Eberl… - Nature, 2021‏ - nature.com
Antibiotics are used to fight pathogens but also target commensal bacteria, disturbing the
composition of gut microbiota and causing dysbiosis and disease. Despite this well-known …

Gut microbiota participates in polystyrene microplastics-induced hepatic injuries by modulating the gut–liver axis

K Zhang, J Yang, L Chen, J He, D Qu, Z Zhang, Y Liu… - ACS …, 2023‏ - ACS Publications
Dietary pollution by polystyrene microplastics (MPs) can cause hepatic injuries and
microbial dysbiosis. Epigallocatechin-3-gallate (EGCG), the major polyphenol in green tea …

Klebsiella oxytoca inhibits Salmonella infection through multiple microbiota-context-dependent mechanisms

L Osbelt, ÉH Almási, M Wende, S Kienesberger… - Nature …, 2024‏ - nature.com
The Klebsiella oxytoca species complex is part of the human microbiome, especially during
infancy and childhood. K. oxytoca species complex strains can produce enterotoxins …

Indole-3-acetic acid alters intestinal microbiota and alleviates ankylosing spondylitis in mice

J Shen, L Yang, K You, T Chen, Z Su, Z Cui… - Frontiers in …, 2022‏ - frontiersin.org
Ankylosing spondylitis (AS) is a systemic, chronic, and inflammatory autoimmune disease
associated with the disorder of intestinal microbiota. Unfortunately, effective therapies for AS …

Lycium ruthenicum Anthocyanins Attenuate High‐Fat Diet‐Induced Colonic Barrier Dysfunction and Inflammation in Mice by Modulating the Gut Microbiota

B Tian, J Zhao, M Zhang, Z Chen, Q Ma… - Molecular Nutrition & …, 2021‏ - Wiley Online Library
Scope Gut barrier dysfunction and inflammation originating from a dysbiotic gut microbiota
(GM) are strongly associated with a high‐fat diet (HFD). Anthocyanins from Lycium …

Akkermansia muciniphila ameliorates acetaminophen-induced liver injury by regulating gut microbial composition and metabolism

J **a, L Lv, B Liu, S Wang, S Zhang, Z Wu… - Microbiology …, 2022‏ - journals.asm.org
The gut microbiota drives individual sensitivity to excess acetaminophen (APAP)-mediated
hepatotoxicity. It has been reported that the bacterium Akkermansia muciniphila protects …

In vitro interaction network of a synthetic gut bacterial community

AS Weiss, AG Burrichter, AC Durai Raj… - The ISME …, 2022‏ - academic.oup.com
A key challenge in microbiome research is to predict the functionality of microbial
communities based on community membership and (meta)-genomic data. As central …

MAIT cells monitor intestinal dysbiosis and contribute to host protection during colitis

Y El Morr, M Fürstenheim, M Mestdagh… - Science …, 2024‏ - science.org
Intestinal inflammation shifts microbiota composition and metabolism. How the host monitors
and responds to such changes remains unclear. Here, we describe a protective mechanism …