Antibiotic resistance is a global health emergency, with resistance detected to all antibiotics
currently in clinical use and only a few novel drugs in the pipeline. Understanding the …

Invasive Staphylococcus aureus infections are common, causing high mortality,
compounded by the propensity of the bacterium to develop drug resistance. S. aureus is an …

Throughout their evolutionary history, bacteria have faced diverse threats from other
microorganisms, including competing bacteria, bacteriophages and predators. In response …

Infections caused by methicillin-resistant Staphylococcus aureus (MRSA) continue to
endanger public health. Here, we report the synthesis of neolignan isomagnolone (I) and its …

Antimicrobial resistance (AMR) is a serious threat to global public health, with approximately
5 million deaths associated with bacterial AMR in 2019. Tackling AMR requires a …

Background Bacterial communities in humans, animals, and the external environment
maintain a large collection of antibiotic resistance genes (ARGs). However, few of these …

The problem of antibiotic resistance among pathogenic bacteria has reached a crisis level.
The treatment options against infections caused by multiple drug-resistant bacteria are …

Antibiotic resistance is a significant global health concern that affects both human and
animal populations. The One Health approach acknowledges the interconnectedness of …

Bacterial biofilms formed by pathogens are known to be hundreds of times more resistant to
antimicrobial agents than planktonic cells, making it extremely difficult to cure biofilm-based …

Most new pathogens of humans and animals arise via switching events from distinct host
species. However, our understanding of the evolutionary and ecological drivers of …