Polymeric nanoparticles have tremendous potential to improve the efficacy of therapeutic
cancer treatments by facilitating targeted delivery to a desired site. The physical and …

Receptor‐mediated drug delivery presents an opportunity to enhance therapeutic efficiency
by accumulating drug within the tissue of interest and reducing undesired, off‐target effects …

Cancer is the cause of death for one in seven individuals worldwide. It is widely
acknowledged that screening and early diagnosis are of vital importance for improving the …

Polymer nanoparticles offer significant benefits for improving delivery of biological
therapeutics such as DNA and proteins, as they allow the cargo to be protected until it is …

Background Despite tremendous advancements in cancer treatment delivery, we are still far
from achieving successful cancer prognosis and cure. The use of new nanocarriers for site …

Peptides have gained increasing interests as drug candidates in modern pharmaceutical
industry, however, the development of peptide drugs acting on intracellular targets is limited …

Nanoparticle technologies intended for human administration must be designed to interact
with, and ideally leverage, a living host environment. Here, we describe smart nanosystems …

Highlights•Targeting specific organelles treat or decrease symptoms of several diseases.•
Manipulation of nanomaterials characteristics can improve the intracellular …

Peptides derived from the third Bcl-2 homology domain (BH3) renormalize apoptotic
signaling by antagonizing prosurvival Bcl-2 family members. These potential peptide drugs …

Historically used for the delivery of hydrophobic drugs through core encapsulation,
amphiphilic copolymer micelles have also more recently appeared as potent nano-systems …