Circular RNAs act as miRNA sponges

AC Panda - Circular RNAs: biogenesis and functions, 2018 - Springer
Majority of RNAs expressed in animal cells lack protein-coding ability. Unlike other cellular
RNAs, circular (circ) RNAs include a large family of noncoding (nc) RNAs that lack the 5′ or …

MicroRNA signatures in human cancers

GA Calin, CM Croce - Nature reviews cancer, 2006 - nature.com
MicroRNA (miRNA) alterations are involved in the initiation and progression of human
cancer. The causes of the widespread differential expression of miRNA genes in malignant …

miRDeep2 accurately identifies known and hundreds of novel microRNA genes in seven animal clades

MR Friedländer, SD Mackowiak, N Li… - Nucleic acids …, 2012 - academic.oup.com
Abstract microRNAs (miRNAs) are a large class of small non-coding RNAs which post-
transcriptionally regulate the expression of a large fraction of all animal genes and are …

Oncomirs—microRNAs with a role in cancer

A Esquela-Kerscher, FJ Slack - Nature reviews cancer, 2006 - nature.com
MicroRNAs (miRNAs) are an abundant class of small non-protein-coding RNAs that function
as negative gene regulators. They regulate diverse biological processes, and bioinformatic …

[HTML][HTML] A mammalian microRNA expression atlas based on small RNA library sequencing

P Landgraf, M Rusu, R Sheridan, A Sewer, N Iovino… - Cell, 2007 - cell.com
MicroRNAs (miRNAs) are small noncoding regulatory RNAs that reduce stability and/or
translation of fully or partially sequence-complementary target mRNAs. In order to identify …

MicroRNA: biogenesis, function and role in cancer

LA MacFarlane, PR Murphy - Current genomics, 2010 - ingentaconnect.com
MicroRNAs are small, highly conserved non-coding RNA molecules involved in the
regulation of gene expression. MicroRNAs are transcribed by RNA polymerases II and III …

[HTML][HTML] microRNAs as oncogenes and tumor suppressors

B Zhang, X Pan, GP Cobb, TA Anderson - Developmental biology, 2007 - Elsevier
microRNAs (miRNAs) are a new class of non-protein-coding, endogenous, small RNAs.
They are important regulatory molecules in animals and plants. miRNA regulates gene …

Post-transcriptional control of miRNA biogenesis

G Michlewski, JF Cáceres - Rna, 2019 - rnajournal.cshlp.org
MicroRNAs (miRNAs) are important regulators of gene expression that bind complementary
target mRNAs and repress their expression. Precursor miRNA molecules undergo nuclear …

Non-coding RNA

JS Mattick, IV Makunin - Human molecular genetics, 2006 - academic.oup.com
The term non-coding RNA (ncRNA) is commonly employed for RNA that does not encode a
protein, but this does not mean that such RNAs do not contain information nor have function …

A MicroRNA signature associated with prognosis and progression in chronic lymphocytic leukemia

GA Calin, M Ferracin, A Cimmino… - … England Journal of …, 2005 - Mass Medical Soc
Background MicroRNA expression profiles can be used to distinguish normal B cells from
malignant B cells in patients with chronic lymphocytic leukemia (CLL). We investigated …