Tetrazole derivatives are a prime class of heterocycles, very important to medicinal
chemistry and drug design due to not only their bioisosterism to carboxylic acid and amide …

Polyheterocycles are one of the most desired synthetic targets due to their numerous and
valuable applications in various fields. Multicomponent reactions (MCRs) are highly …

The assembly of architecturally complex alkaloids embedding the indole nucleus is of
paramount importance for the target oriented synthesis of biologically active molecules. 1 A …

Indoles are some of the most versatile and common nitrogen-based heterocyclic scaffolds
and are frequently used in the synthesis of various organic compounds. Indole based …

Microwave irradiation and post-Ugi reactions own their respective advantages in
comparison with other strategies. The combination of microwave irradiation and post-Ugi …

Bis‐heterocycles (BHCs) are hybrid molecules comprising two linked, bound, spacer, or
fused heterocyclic skeletons. In recent years, these compounds have attracted increased …

A series of 17 indolo/pyrroloazepinone-oxindole conjugates was synthesized and evaluated
for their antiproliferative activity against a panel of selected human cancer cell lines …

Atropisomers have attracted a great deal of attention lately due to their numerous
applications in organic synthesis and to their employment in drug discovery. However, the …

This paper reviews all the syntheses of 7-membered nitrogen heterocycles that are based
on the Ugi multicomponent reaction. Different systems may be obtained in a diversity …

The synthesis of novel 3-tetrazolylmethyl-4H-chromen-4-ones via an Ugi-azide
multicomponent reaction and their biological evaluation against Entamoeba histolytica …