During the last decade, protein analysis and proteomics have been established as new tools
for understanding various biological problems. As the identification of proteins after classical …

Neuropeptides are a complex set of messenger molecules controlling a wide array of
regulatory functions and behaviors within an organism. These neuromodulators are cleaved …

Biomphalaria snails are instrumental in transmission of the human blood fluke Schistosoma
mansoni. With the World Health Organization's goal to eliminate schistosomiasis as a global …

Neurons isolated from Aplysia californica, an organism with a well-defined neural network,
were imaged with secondary ion mass spectrometry, C60-SIMS. A major lipid component of …

The function and activity of almost every circuit in the human brain are modified by the
signaling peptides (SPs) surrounding the neurons. As the complement of peptides can vary …

Background Oysters impart significant socio-ecological benefits from primary production of
food supply, to estuarine ecosystems via reduction of water column nutrients, plankton and …

The first Aplysia californica insulin gene is characterized and its proteolytic processing from
prohormone to final peptides elucidated using a combination of biochemical and mass …

The crustacean stomatogastric ganglion (STG) is modulated by both locally released
neuroactive compounds and circulating hormones. This study presents mass spectrometric …

Peptidomics is the comprehensive characterization of peptides from biological sources
mainly by HPLC and mass spectrometry. Mass spectrometry allows the detection of a …

We use a multidisciplinary approach to identify, map, and characterize the bioactivity of
modulatory neuropeptides in the circuitry that generates feeding behavior in Aplysia. Matrix …