Structural and functional diversity of resistance–nodulation–cell division transporters

PA Klenotic, MA Moseng, CE Morgan, EW Yu - Chemical reviews, 2020 - ACS Publications
Multidrug resistant (MDR) bacteria are a global threat with many common infections
becoming increasingly difficult to eliminate. While significant effort has gone into the …

Lipid transport across bacterial membranes

SI Giacometti, MR MacRae… - Annual Review of …, 2022 - annualreviews.org
The movement of lipids within and between membranes in bacteria is essential for building
and maintaining the bacterial cell envelope. Moving lipids to their final destination is often …

A 'Build and Retrieve'methodology to simultaneously solve cryo-EM structures of membrane proteins

CC Su, M Lyu, CE Morgan, JR Bolla, CV Robinson… - Nature …, 2021 - nature.com
Single-particle cryo-electron microscopy (cryo-EM) has become a powerful technique in the
field of structural biology. However, the inability to reliably produce pure, homogeneous …

Standardized phylogenetic and molecular evolutionary analysis applied to species across the microbial tree of life

M Shakya, SA Ahmed, KW Davenport, MC Flynn… - Scientific reports, 2020 - nature.com
There is growing interest in reconstructing phylogenies from the copious amounts of
genome sequencing projects that target related viral, bacterial or eukaryotic organisms. To …

Genomic analyses of Burkholderia cenocepacia reveal multiple species with differential host-adaptation to plants and humans

A Wallner, E King, ELM Ngonkeu, L Moulin, G Béna - BMC genomics, 2019 - Springer
Background Burkholderia cenocepacia is a human opportunistic pathogen causing
devastating symptoms in patients suffering from immunodeficiency and cystic fibrosis. Out of …

Antibiotic resistance markers in Burkholderia pseudomallei strain Bp1651 identified by genome sequence analysis

JV Bugrysheva, D Sue, JE Gee, MG Elrod… - Antimicrobial agents …, 2017 - Am Soc Microbiol
Burkholderia pseudomallei Bp1651 is resistant to several classes of antibiotics that are
usually effective for treatment of melioidosis, including tetracyclines, sulfonamides, and β …

Crystal structures of the Burkholderia multivorans hopanoid transporter HpnN

N Kumar, CC Su, TH Chou… - Proceedings of the …, 2017 - National Acad Sciences
Strains of the Burkholderia cepacia complex (Bcc) are Gram-negative opportunisitic bacteria
that are capable of causing serious diseases, mainly in immunocompromised individuals …

Co-evolutionary Signals Identify Burkholderia pseudomallei Survival Strategies in a Hostile Environment

C Chewapreecha, J Pensar, S Chattagul… - Molecular Biology …, 2022 - academic.oup.com
The soil bacterium Burkholderia pseudomallei is the causative agent of melioidosis and a
significant cause of human morbidity and mortality in many tropical and subtropical …

Pan-Genome Analysis Reveals Host-Specific Functional Divergences in Burkholderia gladioli

HH Lee, J Park, H Jung, YS Seo - Microorganisms, 2021 - mdpi.com
Burkholderia gladioli has high versatility and adaptability to various ecological niches. Here,
we constructed a pan-genome using 14 genome sequences of B. gladioli, which originate …

Unprecedented melioidosis cases in northern Australia caused by an Asian Burkholderia pseudomallei strain identified by using large-scale comparative genomics

EP Price, DS Sarovich, EJ Smith… - Applied and …, 2016 - Am Soc Microbiol
Melioidosis is a disease of humans and animals that is caused by the saprophytic bacterium
Burkholderia pseudomallei. Once thought to be confined to certain locations, the known …