[HTML][HTML] Current insights on antifungal therapy: Novel nanotechnology approaches for drug delivery systems and new drugs from natural sources

F Sousa, D Ferreira, S Reis, P Costa - Pharmaceuticals, 2020 - mdpi.com
The high incidence of fungal infections has become a worrisome public health issue, having
been aggravated by an increase in host predisposition factors. Despite all the drugs …

New strategies for local treatment of vaginal infections

R Palmeira-de-Oliveira, A Palmeira-de-Oliveira… - Advanced drug delivery …, 2015 - Elsevier
Vaginal infections are extremely prevalent, particularly among women of reproductive age.
Although they do not result in high mortality rates, these infections are associated with high …

Development and in vitro/in vivo evaluation of pH-sensitive polymeric nanoparticles loaded hydrogel for the management of psoriasis

MI Asad, D Khan, AU Rehman, A Elaissari, N Ahmed - Nanomaterials, 2021 - mdpi.com
Methotrexate (MTX), the gold standard against psoriasis, poses severe problems when
administered systemically viz increased toxicity, poor solubility and adverse reactions …

Synthesis and characterization of new functionalized chitosan and its antimicrobial and in-vitro release behavior from topical gel

AE Mohamed, WE Elgammal, AM Eid… - International Journal of …, 2022 - Elsevier
Recently, chitosan and its derivatives have been gaining more attention due to their high
integration into various biomedical applications. Herein, a new chitosan derivative was …

Bioadhesive hydrogels for cosmetic applications

ME Parente, A Ochoa Andrade, G Ares… - … journal of cosmetic …, 2015 - Wiley Online Library
Introduction The use of bioadhesive hydrogels for skin care presents important advantages
such as long residence times on the application site and reduced product administration …

[PDF][PDF] Formulation and evaluation of fluconazole topical gel

DA Helal, DABD El-Rhman, SA Abdel-Halim… - Int J Pharm Pharm …, 2012 - scholar.archive.org
Fluconazole is an imidazole derivative used for the treatment of local and systemic fungal
infection. The oral use of fluconazole is not recommended as it has many side effects. The …

[HTML][HTML] Nanostructured lipid carriers to enhance the bioavailability and solubility of ranolazine: Statistical optimization and pharmacological evaluations

A Unnisa, AK Chettupalli, RS Alazragi, W Alelwani… - Pharmaceuticals, 2023 - mdpi.com
Chronic stable angina pectoris is the primary indication for ranolazine (RZ), an anti-anginal
drug. The drug has an anti-ischemic action that is unaffected by either blood pressure or …

Terpene microemulsions for transdermal curcumin delivery: effects of terpenes and cosurfactants

CH Liu, FY Chang, DK Hung - Colloids and Surfaces B: Biointerfaces, 2011 - Elsevier
Microemulsion systems composed of terpenes, polysorbate 80, cosurfactants, and water
were investigated as transdermal delivery vehicles for curcumin. Pseudoternary phase …

Vaginal mucoadhesive drug delivery systems

RR de Araújo Pereira, ML Bruschi - Drug development and …, 2012 - Taylor & Francis
Background: The vaginal mucosal cavity is a feasible, safe, very attractive site for drug
delivery and highly dynamic with respect to absorption of drugs, their metabolism and their …

Design, formulation and optimization of novel soft nano-carriers for transdermal olmesartan medoxomil delivery: In vitro characterization and in vivo pharmacokinetic …

M Kamran, A Ahad, M Aqil, SS Imam, Y Sultana… - International journal of …, 2016 - Elsevier
Olmesartan is a hydrophobic antihypertensive drug with a short biological half-life, and low
bioavailability, presents a challenge with respect to its oral administration. The objective of …