High-valent metal–oxo species with multiply-bonded M–O groups have been proposed as
key intermediates in many biological and abiological catalytic oxidation reactions. These …

On the basis of its generally accessible I/II redox couple and bioavailability, copper plays a
wide variety of roles in nature that mostly involve electron transfer (ET), O 2 binding …

Copper is one of the most abundant and less toxic transition metals. Nature takes advantage
of the bioavailability and rich redox chemistry of Cu to carry out oxygenase and oxidase …

Selective functionalization of unactivated C–H bonds, water oxidation, and dioxygen
reduction are extremely important reactions in the context of finding energy carriers and …

Two are better than one: Quantum mechanics/molecular mechanics (QM/MM) methods are
the state‐of‐the‐art computational technique for treating reactive and other “electronic” …

Heme-copper oxidases (HCOs) are terminal enzymes on the mitochondrial or bacterial
respiratory electron transport chain, which utilize a unique heterobinuclear active site to …

The selective functionalization of strong C− H bonds and the oxidation of water by cheap
and nontoxic metals are some of the key targets of chemical research today. It has been …

Alkanes constitute the cheapest and most abundant feedstock for organic chemicals.
However, the redistribution of CsC and CsH bonds in hydrocarbons into more sophisticated …

The development of processes for selective hydrocarbon oxidation is a goal that has long
been pursued. An additional challenge is to make such processes environmentally friendly …

For decades, the enzymatic conversion of cellulose was thought to rely on the synergistic
action of hydrolytic enzymes, but recent work has shown that lytic polysaccharide …