Artificial intelligence as the next step towards precision pathology

B Acs, M Rantalainen, J Hartman - Journal of internal medicine, 2020 - Wiley Online Library
Pathology is the cornerstone of cancer care. The need for accuracy in histopathologic
diagnosis of cancer is increasing as personalized cancer therapy requires accurate …

[HTML][HTML] Introduction to digital image analysis in whole-slide imaging: a white paper from the digital pathology association

F Aeffner, MD Zarella, N Buchbinder, MM Bui… - Journal of pathology …, 2019 - Elsevier
The advent of whole-slide imaging in digital pathology has brought about the advancement
of computer-aided examination of tissue via digital image analysis. Digitized slides can now …

[HTML][HTML] Ki67 reproducibility using digital image analysis: an inter-platform and inter-operator study

B Acs, V Pelekanou, Y Bai, S Martinez-Morilla… - Laboratory …, 2019 - Elsevier
Ki67 expression has been a valuable prognostic variable in breast cancer, but has not seen
broad adoption due to lack of standardization between institutions. Automation could …

[HTML][HTML] Histopathological images analysis and predictive modeling implemented in digital pathology—current affairs and perspectives

M Moscalu, R Moscalu, CG Dascălu, V Țarcă… - Diagnostics, 2023 - mdpi.com
In modern clinical practice, digital pathology has an essential role, being a technological
necessity for the activity in the pathological anatomy laboratories. The development of …

Analytical validation of a standardised scoring protocol for Ki67 immunohistochemistry on breast cancer excision whole sections: an international multicentre …

SCY Leung, TO Nielsen, LA Zabaglo, I Arun… - …, 2019 - Wiley Online Library
Aims The nuclear proliferation marker Ki67 assayed by immunohistochemistry has multiple
potential uses in breast cancer, but an unacceptable level of interlaboratory variability has …

Applications of artificial intelligence in breast pathology

Y Liu, D Han, AV Parwani, Z Li - Archives of Pathology & …, 2023 - meridian.allenpress.com
Context.—Increasing implementation of whole slide imaging together with digital workflow
and advances in computing capacity enable the use of artificial intelligence (AI) in …

Systematically higher Ki67 scores on core biopsy samples compared to corresponding resection specimen in breast cancer: a multi-operator and multi-institutional …

B Acs, SCY Leung, KM Kidwell, I Arun, R Augulis… - Modern …, 2022 - nature.com
Ki67 has potential clinical importance in breast cancer but has yet to see broad acceptance
due to inter-laboratory variability. Here we tested an open source and calibrated automated …

International guidelines for veterinary tumor pathology: a call to action

DJ Meuten, FM Moore, TA Donovan… - Veterinary …, 2021 - journals.sagepub.com
Standardization of tumor assessment lays the foundation for validation of grading systems,
permits reproducibility of oncologic studies among investigators, and increases confidence …