Choosing the right cell line for breast cancer research
DL Holliday, V Speirs - Breast cancer research, 2011 - Springer
Breast cancer is a complex and heterogeneous disease. Gene expression profiling has
contributed significantly to our understanding of this heterogeneity at a molecular level …
contributed significantly to our understanding of this heterogeneity at a molecular level …
Long-term culture, genetic manipulation and xenotransplantation of human normal and breast cancer organoids
Organoid technology has revolutionized the study of human organ development, disease
and therapy response tailored to the individual. Although detailed protocols are available for …
and therapy response tailored to the individual. Although detailed protocols are available for …
A living biobank of breast cancer organoids captures disease heterogeneity
Breast cancer (BC) comprises multiple distinct subtypes that differ genetically,
pathologically, and clinically. Here, we describe a robust protocol for long-term culturing of …
pathologically, and clinically. Here, we describe a robust protocol for long-term culturing of …
Identification of gastric cancer stem cells using the cell surface marker CD44
S Takaishi, T Okumura, S Tu, SSW Wang… - Stem …, 2009 - academic.oup.com
Cancer stem cells (CSCs) have been defined as a unique subpopulation in tumors that
possess the ability to initiate tumor growth and sustain tumor self-renewal. Although the …
possess the ability to initiate tumor growth and sustain tumor self-renewal. Although the …
Biomimetic nanotechnology toward personalized vaccines
While traditional approaches for disease management in the era of modern medicine have
saved countless lives and enhanced patient well‐being, it is clear that there is significant …
saved countless lives and enhanced patient well‐being, it is clear that there is significant …
[HTML][HTML] Histological types of breast cancer: how special are they?
B Weigelt, FC Geyer, JS Reis-Filho - Molecular oncology, 2010 - Elsevier
Breast cancer is a heterogeneous disease, comprising multiple entities associated with
distinctive histological and biological features, clinical presentations and behaviours and …
distinctive histological and biological features, clinical presentations and behaviours and …
Three-dimensional printing of Hela cells for cervical tumor model in vitro
Advances in three-dimensional (3D) printing have enabled the direct assembly of cells and
extracellular matrix materials to form in vitro cellular models for 3D biology, the study of …
extracellular matrix materials to form in vitro cellular models for 3D biology, the study of …
Molecular profiling of breast cancer cell lines defines relevant tumor models and provides a resource for cancer gene discovery
Background Breast cancer cell lines have been used widely to investigate breast cancer
pathobiology and new therapies. Breast cancer is a molecularly heterogeneous disease …
pathobiology and new therapies. Breast cancer is a molecularly heterogeneous disease …
[HTML][HTML] The past, present, and future of breast cancer models for nanomedicine development
P Boix-Montesinos, PM Soriano-Teruel… - Advanced drug delivery …, 2021 - Elsevier
Even given recent advances in nanomedicine development of breast cancer treatment in
recent years and promising results in pre-clinical models, cancer nanomedicines often fail at …
recent years and promising results in pre-clinical models, cancer nanomedicines often fail at …
Progress in the understanding of the mechanism of tamoxifen resistance in breast cancer
J Yao, K Deng, J Huang, R Zeng, J Zuo - Frontiers in pharmacology, 2020 - frontiersin.org
Tamoxifen is a drug commonly used in the treatment of breast cancer, especially for
postmenopausal patients. However, its efficacy is limited by the development of drug …
postmenopausal patients. However, its efficacy is limited by the development of drug …