A decade of advances in single‐cell nanocoating for mammalian cells

H Lee, N Kim, HB Rheem, BJ Kim… - Advanced Healthcare …, 2021‏ - Wiley Online Library
Strategic advances in the single‐cell nanocoating of mammalian cells have noticeably been
made during the last decade, and many potential applications have been demonstrated …

Development of oleanane-type triterpenes as a new class of HCV entry inhibitors

F Yu, QI Wang, Z Zhang, Y Peng, Y Qiu… - Journal of Medicinal …, 2013‏ - ACS Publications
Development of hepatitis C virus (HCV) entry inhibitors represents an emerging approach
that satisfies a tandem mechanism for use with other inhibitors in a multifaceted cocktail. By …

Design, synthesis, and biological evaluations of tumor-targeting dual-warhead conjugates for a taxoid–camptothecin combination chemotherapy

JG Vineberg, ES Zuniga, A Kamath… - Journal of medicinal …, 2014‏ - ACS Publications
Novel tumor-targeting dual-warhead conjugates, 2 (DW-1) and 3 (DW-2), which consist of a
next-generation taxoid, 1 (SB-T-1214), and camptothecin as two warheads, self-immolative …

Subcellular fate of a fluorescent cholesterol-poly (ethylene glycol) conjugate: An excellent plasma membrane imaging reagent

X Chen, X Zhang, HY Wang, Z Chen, FG Wu - Langmuir, 2016‏ - ACS Publications
Cholesterol-containing molecules or nanoparticles play a significant role in achieving
favorable plasma membrane imaging and efficient cellular uptake of drugs by the excellent …

[PDF][PDF] Ordas

HR Zope, F Versluis - … Spaink, HP, & …, 2013‏ - scholarlypublications …
The molecular building blocks available in biological systems self-assemble into defined
structures in an extremely controlled manner. These structures must be flexible and adaptive …

Strategies for cell membrane functionalization

JPK Armstrong, AW Perriman - Experimental Biology and …, 2016‏ - journals.sagepub.com
The ability to rationally manipulate and augment the cytoplasmic membrane can be used to
overcome many of the challenges faced by conventional cellular therapies and provide …

Catalytic Modification of Dehydroalanine in Peptides and Proteins by Palladium‐Mediated Cross‐Coupling

AD de Bruijn, G Roelfes - Chemistry–A European Journal, 2018‏ - Wiley Online Library
Dehydroalanine (Dha) is a remarkably versatile non‐canonical amino acid often found in
antimicrobial peptides. Herein, we present the catalytic modification of Dha by a palladium …

Holistic approach of Swiss fetal progenitor cell banking: Optimizing safe and sustainable substrates for regenerative medicine and biotechnology

A Laurent, N Hirt-Burri, C Scaletta, M Michetti… - … in bioengineering and …, 2020‏ - frontiersin.org
Safety, quality, and regulatory-driven iterative optimization of therapeutic cell source
selection has constituted the core developmental bedrock for primary fetal progenitor cell …

Design, synthesis and application of fluorine-labeled taxoids as 19F NMR probes for the metabolic stability assessment of tumor-targeted drug delivery systems

JD Seitz, JG Vineberg, L Wei, JF Khan… - Journal of fluorine …, 2015‏ - Elsevier
Novel tumor-targeting drug conjugates, BLT-F 2 (1) and BLT-SF 6 (2), bearing a fluorotaxoid
as the warhead, a mechanism-based self-immolative disulfide linker, and biotin as the tumor …

Plasma membrane functionalization using highly fusogenic immune activator liposomes

E Naumovska, S Ludwanowski, N Hersch, T Braun… - Acta biomaterialia, 2014‏ - Elsevier
Cell surface functionalization and target molecule incorporation into living cell membranes
without functional damage represent major biotechnological challenges. One possible way …